TY - JOUR
T1 - Acute thrombocytopenia
T2 - An unusual complication occurring after drug-eluting microspheres transcatheter hepatic chemoembolization
AU - Poggi, Guido
AU - Quaretti, Pietro
AU - Montagna, Benedetta
AU - Sottotetti, Federico
AU - Tagliaferri, Barbara
AU - Pozzi, Emma
AU - Amatu, Alessio
AU - Pagella, Chiara
AU - Bernardo, Giovanni
PY - 2011/2
Y1 - 2011/2
N2 - Image-guided transcatheter hepatic chemoembolization (TACE) is accepted worldwide as an effective treatment for patients with unresectable hepatocellular carcinoma and liver metastases from neuroendocrine tumors, colorectal carcinomas, and uveal melanomas. Although the technique is relatively safe, it has been associated with several complications. We report the cases of two patients with colorectal liver metastases who developed acute thrombocytopenia a few hours after TACE. To our knowledge, acute thrombocytopenia occurring after TACE with drug-eluting microspheres has not yet been reported. Here we discuss the hypothetical etiopathogenetic mechanisms.
AB - Image-guided transcatheter hepatic chemoembolization (TACE) is accepted worldwide as an effective treatment for patients with unresectable hepatocellular carcinoma and liver metastases from neuroendocrine tumors, colorectal carcinomas, and uveal melanomas. Although the technique is relatively safe, it has been associated with several complications. We report the cases of two patients with colorectal liver metastases who developed acute thrombocytopenia a few hours after TACE. To our knowledge, acute thrombocytopenia occurring after TACE with drug-eluting microspheres has not yet been reported. Here we discuss the hypothetical etiopathogenetic mechanisms.
KW - Arteries
KW - Chemotherapeutic embolization
KW - Interventional procedures
KW - Liver neoplasms
KW - Therapy liver
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U2 - 10.1007/s00270-010-9983-y
DO - 10.1007/s00270-010-9983-y
M3 - Article
C2 - 20848100
AN - SCOPUS:79959771559
VL - 34
JO - CardioVascular and Interventional Radiology
JF - CardioVascular and Interventional Radiology
SN - 7415-5101
IS - SUPPL. 2
ER -