Acute thrombocytopenia: An unusual complication occurring after drug-eluting microspheres transcatheter hepatic chemoembolization

Guido Poggi; Pietro Quaretti; Benedetta Montagna; Federico Sottotetti; Barbara Tagliaferri; Emma Pozzi; Alessio Amatu; Chiara Pagella; Giovanni Bernardo

doi:10.1007/s00270-010-9983-y

Acute thrombocytopenia: An unusual complication occurring after drug-eluting microspheres transcatheter hepatic chemoembolization

Guido Poggi, Pietro Quaretti, Benedetta Montagna, Federico Sottotetti, Barbara Tagliaferri, Emma Pozzi, Alessio Amatu, Chiara Pagella, Giovanni Bernardo

Research output: Contribution to journal › Article › peer-review

Abstract

Image-guided transcatheter hepatic chemoembolization (TACE) is accepted worldwide as an effective treatment for patients with unresectable hepatocellular carcinoma and liver metastases from neuroendocrine tumors, colorectal carcinomas, and uveal melanomas. Although the technique is relatively safe, it has been associated with several complications. We report the cases of two patients with colorectal liver metastases who developed acute thrombocytopenia a few hours after TACE. To our knowledge, acute thrombocytopenia occurring after TACE with drug-eluting microspheres has not yet been reported. Here we discuss the hypothetical etiopathogenetic mechanisms.

Original language	English
Journal	CardioVascular and Interventional Radiology
Volume	34
Issue number	SUPPL. 2
DOIs	https://doi.org/10.1007/s00270-010-9983-y
Publication status	Published - Feb 2011

Keywords

Arteries
Chemotherapeutic embolization
Interventional procedures
Liver neoplasms
Therapy liver

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging
Cardiology and Cardiovascular Medicine

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10.1007/s00270-010-9983-y

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Acute thrombocytopenia : An unusual complication occurring after drug-eluting microspheres transcatheter hepatic chemoembolization. / Poggi, Guido; Quaretti, Pietro; Montagna, Benedetta; Sottotetti, Federico ; Tagliaferri, Barbara; Pozzi, Emma; Amatu, Alessio; Pagella, Chiara; Bernardo, Giovanni.

In: CardioVascular and Interventional Radiology, Vol. 34, No. SUPPL. 2, 02.2011.

Research output: Contribution to journal › Article › peer-review

Poggi, Guido ; Quaretti, Pietro ; Montagna, Benedetta ; Sottotetti, Federico ; Tagliaferri, Barbara ; Pozzi, Emma ; Amatu, Alessio ; Pagella, Chiara ; Bernardo, Giovanni. / Acute thrombocytopenia : An unusual complication occurring after drug-eluting microspheres transcatheter hepatic chemoembolization. In: CardioVascular and Interventional Radiology. 2011 ; Vol. 34, No. SUPPL. 2.

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AU - Quaretti, Pietro

AU - Montagna, Benedetta

AU - Sottotetti, Federico

AU - Tagliaferri, Barbara

AU - Pozzi, Emma

AU - Amatu, Alessio

AU - Pagella, Chiara

AU - Bernardo, Giovanni

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AB - Image-guided transcatheter hepatic chemoembolization (TACE) is accepted worldwide as an effective treatment for patients with unresectable hepatocellular carcinoma and liver metastases from neuroendocrine tumors, colorectal carcinomas, and uveal melanomas. Although the technique is relatively safe, it has been associated with several complications. We report the cases of two patients with colorectal liver metastases who developed acute thrombocytopenia a few hours after TACE. To our knowledge, acute thrombocytopenia occurring after TACE with drug-eluting microspheres has not yet been reported. Here we discuss the hypothetical etiopathogenetic mechanisms.

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KW - Chemotherapeutic embolization

KW - Interventional procedures

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Acute thrombocytopenia: An unusual complication occurring after drug-eluting microspheres transcatheter hepatic chemoembolization

Abstract

Keywords

ASJC Scopus subject areas

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