Abstract
We describe a patient with gross hematuria, severe renal failure and symptoms suggestive of systemic vasculitis. Renal biopsy showed very focal and segmental necrotizing glomerulonephritis without crescents. A few C3 deposits were seen by immunofluorescence. The tubular lesions, on the contrary, were very severe, consisting of tubular cell necrosis and ruptured tubular basement membrane, associated with large numbers of intraluminal erythrocytes and erythrocytic casts. After gross hematuria had cleared, renal function slowly recovered. Because of biopsy findings and clinical course, acute renal failure in this patient was considered to be due to the tubular lesions caused by gross hematuria.
| Original language | English |
|---|---|
| Pages (from-to) | 102-105 |
| Number of pages | 4 |
| Journal | Nephron |
| Volume | 61 |
| Issue number | 1 |
| Publication status | Published - 1992 |
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Keywords
- Acute renal failure
- Acute tubular necrosis
- Hematuria
- Necrotizing glomerulonephritis
ASJC Scopus subject areas
- Nephrology
Cite this
Acute tubular necrosis caused by gross hematuria in a patient with focal and segmental necrotizing glomerulonephritis. / Fogazzi, G. B.; Banfi, G.; Ponticelli, C.
In: Nephron, Vol. 61, No. 1, 1992, p. 102-105.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Acute tubular necrosis caused by gross hematuria in a patient with focal and segmental necrotizing glomerulonephritis
AU - Fogazzi, G. B.
AU - Banfi, G.
AU - Ponticelli, C.
PY - 1992
Y1 - 1992
N2 - We describe a patient with gross hematuria, severe renal failure and symptoms suggestive of systemic vasculitis. Renal biopsy showed very focal and segmental necrotizing glomerulonephritis without crescents. A few C3 deposits were seen by immunofluorescence. The tubular lesions, on the contrary, were very severe, consisting of tubular cell necrosis and ruptured tubular basement membrane, associated with large numbers of intraluminal erythrocytes and erythrocytic casts. After gross hematuria had cleared, renal function slowly recovered. Because of biopsy findings and clinical course, acute renal failure in this patient was considered to be due to the tubular lesions caused by gross hematuria.
AB - We describe a patient with gross hematuria, severe renal failure and symptoms suggestive of systemic vasculitis. Renal biopsy showed very focal and segmental necrotizing glomerulonephritis without crescents. A few C3 deposits were seen by immunofluorescence. The tubular lesions, on the contrary, were very severe, consisting of tubular cell necrosis and ruptured tubular basement membrane, associated with large numbers of intraluminal erythrocytes and erythrocytic casts. After gross hematuria had cleared, renal function slowly recovered. Because of biopsy findings and clinical course, acute renal failure in this patient was considered to be due to the tubular lesions caused by gross hematuria.
KW - Acute renal failure
KW - Acute tubular necrosis
KW - Hematuria
KW - Necrotizing glomerulonephritis
UR - http://www.scopus.com/inward/record.url?scp=0026538055&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0026538055&partnerID=8YFLogxK
M3 - Article
C2 - 1528328
AN - SCOPUS:0026538055
VL - 61
SP - 102
EP - 105
JO - Experimental Nephrology
JF - Experimental Nephrology
SN - 0028-2766
IS - 1
ER -