Encefalomielite acuta disseminata: Descrizione di un caso clinico pediatrico con ritenzione urinaria acuta

Translated title of the contribution: Acute urinary retention in a child with acute disseminated encephalomyelitis

L. Doria Lamba, E. De Grandis, E. De Negri, L. Montaldi, P. Grosso, M. G. Marazzi, A. Rossi, P. Tuo

Research output: Contribution to journalArticlepeer-review

Abstract

Acute disseminated encephalomyelitis (ADEM) is an immune-mediated inflammatory demyelinating encephalomyelitis with often monosymptomatic abrupt onset, followed by multifocal neurologic symptomatology depending on lesion-site. Diagnosis is made on the basis of characteristic magnetic resonance imaging (MRI) signal alterations. ADEM is sensitive to steroid therapy, immunoglobulins and plasmapheresis, presents usually a monophasic course and disappears completely after 2 or 3 weeks. Resolution of MRI lesions appears usually within 6 months of presentation. We report on a 14-year-old male, admitted to our Emergency Unit because of fever and acute urinary retention with a normal neurological examination. Urinary tract ultrasonography and mictional cystography were normal; electrophysiology showed a mild involvement of the peripheral nervous system and brain and spine MRI revealed disseminated areas of increased signal on T2-weighted sequences suggestive of ADEM. Steroid therapy brought about clinical recovery in a few days. Resolution of lesions on MRI after 4 months and absence of relapses during four-year clinical follow-up confirmed definitive diagnosis. Our case is interesting because, to our knowledge, this is the first literature report with acute urinary retention as predominant symptom in monosymptomatic forms. Another peculiar feature is the absence of associated neurologic symptomatology despite MRI evidence of important brain and spine alterations.

Translated title of the contributionAcute urinary retention in a child with acute disseminated encephalomyelitis
Original languageItalian
Pages (from-to)305-309
Number of pages5
JournalMinerva Pediatrica
Volume58
Issue number3
Publication statusPublished - Jun 2006

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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