Adaptability to changes in temporal structure is fornix-dependent

Sze Chai Kwok, Anna S. Mitchell, Mark J. Buckley

Research output: Contribution to journalArticlepeer-review

Abstract

Recognition memory deficits, even after short delays, are sometimes observed following hippocampal damage. One hypothesis links the hippocampus with processes in updating contextual memory representation. Here, we used fornix transection, which partially disconnects the hippocampal system, and compares the performance of fornix-transected monkeys with normal monkeys on two versions of a delayed-matching-to-position task with short delays. Spatial recognition memory was affected by fornix transection only when the temporal structure of the task changed across trials, while differences in motor control, motivation, perception, or short-term memory were not critical. We attributed the deficit to a compromised ability in tracking changes in task temporal structure.

Original languageEnglish
Pages (from-to)354-359
Number of pages6
JournalLearning and Memory
Volume22
Issue number8
DOIs
Publication statusPublished - Aug 1 2015

ASJC Scopus subject areas

  • Cognitive Neuroscience
  • Cellular and Molecular Neuroscience
  • Neuropsychology and Physiological Psychology

Fingerprint

Dive into the research topics of 'Adaptability to changes in temporal structure is fornix-dependent'. Together they form a unique fingerprint.

Cite this