TY - JOUR
T1 - Adaptive servo ventilation reduces central sleep apnea in chronic heart failure patients
T2 - Beneficial effects on autonomic modulation of heart rate
AU - D'Elia, Emilia
AU - Vanoli, Emilio
AU - La Rovere, Maria T.
AU - Fanfulla, Francesco
AU - Maggioni, Alessandra
AU - Casali, Valentina
AU - Damiano, Simona
AU - Specchia, Giuseppe
AU - Mortara, Andrea
PY - 2013/4
Y1 - 2013/4
N2 - AIM: Adaptive servo ventilation (ASV) is a method of ventilator support aimed to treat central sleep apnea (CSA). We investigated the effects of an acute use of ASV in chronic heart failure (CHF) patients with CSA and the potential influence on sympathetic nerve activity. METHODS: Patients were studied with ambulatory cardio-respiratory 24 Holter (Somtè) recording of air flow, ECG and oxygen saturation. Comparison before and after ASV treatment was made for apnea index (AI), apnea-hypopnea index (AHI), pulse oxygen saturation, desaturation related to apnea, heart rate (HR) and heart rate variability (HRV). RESULTS: Seventeen patients were enrolled. At baseline, apnea index and apnea-hypopnea index were, respectively, 16.92±7.8 and 41.37±17.5. During ASV, they significantly decreased to 0.06±0.0 (P
AB - AIM: Adaptive servo ventilation (ASV) is a method of ventilator support aimed to treat central sleep apnea (CSA). We investigated the effects of an acute use of ASV in chronic heart failure (CHF) patients with CSA and the potential influence on sympathetic nerve activity. METHODS: Patients were studied with ambulatory cardio-respiratory 24 Holter (Somtè) recording of air flow, ECG and oxygen saturation. Comparison before and after ASV treatment was made for apnea index (AI), apnea-hypopnea index (AHI), pulse oxygen saturation, desaturation related to apnea, heart rate (HR) and heart rate variability (HRV). RESULTS: Seventeen patients were enrolled. At baseline, apnea index and apnea-hypopnea index were, respectively, 16.92±7.8 and 41.37±17.5. During ASV, they significantly decreased to 0.06±0.0 (P
KW - Central sleep apnea
KW - Chronic heart failure
KW - Heart rate
KW - Heart rate variability
KW - Oxygen saturation
KW - Sympathetic nervous system
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U2 - 10.2459/JCM.0b013e32835364b2
DO - 10.2459/JCM.0b013e32835364b2
M3 - Article
C2 - 22498996
AN - SCOPUS:84875210681
VL - 14
SP - 296
EP - 300
JO - Journal of Cardiovascular Medicine
JF - Journal of Cardiovascular Medicine
SN - 1558-2027
IS - 4
ER -