Adaptive threshold method based on PET measured lesion-to-background ratio for the estimation of Metabolic Target Volume from 18F-FDG PET images

Francesca Gallivanone, Federico Fazio, Luca Presotto, Maria C. Gilardi, Carla Canevari, Isabella Castiglioni

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Most advanced radiotherapy planning can be optimized by incorporating the metabolic image of the tumour to be irradiated (Metabolic Target Volume). MTV can be properly obtained by in vivo molecular imaging studies as the volume of metabolically active tumour component. Positron EmissionTomography (PET) can provide MTV by in vivo measuring the glucose metabolism of a tumour. Aim of this work was to develop an innovative PET image segmentation method, based on an adaptive threshold of the image signal-to-noise ratio, for the estimation of the MTV. The proposed method was tested on a set of anthropomorphic phantoms proving its feasibility, operator-independency and accuracy in a clinical setting.

Original languageEnglish
Title of host publicationIEEE Nuclear Science Symposium Conference Record
PublisherInstitute of Electrical and Electronics Engineers Inc.
ISBN (Print)9781479905348
DOIs
Publication statusPublished - 2013
Event2013 60th IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2013 - Seoul, Korea, Republic of
Duration: Oct 27 2013Nov 2 2013

Other

Other2013 60th IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2013
CountryKorea, Republic of
CitySeoul
Period10/27/1311/2/13

ASJC Scopus subject areas

  • Radiation
  • Nuclear and High Energy Physics
  • Radiology Nuclear Medicine and imaging

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