Il valore aggiunto della SPECT/CT rispetto all'imaging planare nel migliorare la ricerca del linfonodo sentinella in pazienti con carcinoma mammario

Translated title of the contribution: Added value of SPECT/CT over planar imaging in improving sentinel node detection in breast cancer patients

Vincenzo Frusciante, Artor Niccoli Asabella, Gaetano Castriotta, Michele Guerra, Roberto Murgo, Luigi Ciuffreda, Valentina Lavelli, Cristina Ferrari, Giuseppe Rubini

Research output: Contribution to journalArticle


The aim of the study was to assess the diagnostic contribution of hybrid SPECT/CT lymphoscintigraphy compared to planar imaging for the correct identifcation of sentinel lymph nodes (SLN) in breast cancer (BC) patients. Materials and methods. 73 planar and SPECT/CT lymphoscintigraphies were performed in 70 consecutive patients with BC (70 women, mean age 55.7±12.0 years, range 26-84) for pre-surgical SLNs research. Cohen'K was performed to evaluate the agreement between both techniques; their diagnostic capability was evaluated by the Student's t-test for paired data. Results. In 54/73 (73.9%) lymphoscintigraphies, SLNs were detected both on planar and SPECT/CT images. In 19/73 (26.1%) discordant cases, planar technique showed a higher number of SLNs in 4/19 lymphoscintigraphies, while SPECT/CT in 15/19. Radio-guided surgery confrmed SPECT/CT fndings. Concordance between the two techniques was poor (K=-0.095). Overall, SPECT/CT detected 13 SLNs more than planar imaging (p=0.07). Furthermore, in 17/73 (23.2%) lymphoscintigraphies, SPECT/CT defned the exact SLNs anatomical localization, equivocal on planar images. Conclusions. SPECT/CT demonstrated added value over planar imaging, providing more information for the best surgical approach. It is useful especially in patients with negative or doubt planar imaging.

Original languageItalian
Pages (from-to)444-449
Number of pages6
JournalRecenti Progressi in Medicina
Issue number8
Publication statusPublished - Aug 1 2016


ASJC Scopus subject areas

  • Medicine(all)

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