Additional pulmonary blood flow in the cavopulmonary anastomosis by means of a modified Blalock-Taussig shunt: Is it a beneficial clinical option?

Giuseppe D'Avenio, Antonio Amodeo, Mauro Grigioni

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Since many years, patients with functionally single ventricles are subjected to surgical operations, meant to create a more favourable haemodynamics. The bidirectional cavopulmonary anastomosis (BCPA) is one of such operations, and is principally meant to prepare a future total cavopulmonary anastomosis, i.e., the direct connection of the two vene cavae to the pulmonary arteries. Since the circulation ensuing from a BCPA is basically composed of two circuits in parallel, the upper and the lower circulation, the latter being external to the lung perfusion, there is a potential problem of low oxygen saturation. It has been proposed that an additional pulmonary blood flow, such as that imparted by a modified Blalock-Taussig shunt could be beneficial as for the oxygen saturation. In the present study, this hypothesis is verified by means of a lumped parameter model, considering different degrees of shunting. The results support the view that an additional source of blood flow can have a beneficial effect on the pediatric patient operated on with a BCPA. Future comparison of numerical results with actual clinical data will allow to evaluate the predictive capabilities of the model.

Original languageEnglish
Title of host publicationBIOSIGNALS 2013 - Proceedings of the International Conference on Bio-Inspired Systems and Signal Processing
Pages392-395
Number of pages4
Publication statusPublished - 2013
EventInternational Conference on Bio-Inspired Systems and Signal Processing, BIOSIGNALS 2013 - Barcelona, Spain
Duration: Feb 11 2013Feb 14 2013

Other

OtherInternational Conference on Bio-Inspired Systems and Signal Processing, BIOSIGNALS 2013
CountrySpain
CityBarcelona
Period2/11/132/14/13

Fingerprint

Blood
Pediatrics
Oxygen
Hemodynamics
Networks (circuits)

Keywords

  • Cardiac surgery
  • Congenital heart disease
  • Mathematical modelling

ASJC Scopus subject areas

  • Biomedical Engineering
  • Signal Processing

Cite this

D'Avenio, G., Amodeo, A., & Grigioni, M. (2013). Additional pulmonary blood flow in the cavopulmonary anastomosis by means of a modified Blalock-Taussig shunt: Is it a beneficial clinical option? In BIOSIGNALS 2013 - Proceedings of the International Conference on Bio-Inspired Systems and Signal Processing (pp. 392-395)

Additional pulmonary blood flow in the cavopulmonary anastomosis by means of a modified Blalock-Taussig shunt : Is it a beneficial clinical option? / D'Avenio, Giuseppe; Amodeo, Antonio; Grigioni, Mauro.

BIOSIGNALS 2013 - Proceedings of the International Conference on Bio-Inspired Systems and Signal Processing. 2013. p. 392-395.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

D'Avenio, G, Amodeo, A & Grigioni, M 2013, Additional pulmonary blood flow in the cavopulmonary anastomosis by means of a modified Blalock-Taussig shunt: Is it a beneficial clinical option? in BIOSIGNALS 2013 - Proceedings of the International Conference on Bio-Inspired Systems and Signal Processing. pp. 392-395, International Conference on Bio-Inspired Systems and Signal Processing, BIOSIGNALS 2013, Barcelona, Spain, 2/11/13.
D'Avenio G, Amodeo A, Grigioni M. Additional pulmonary blood flow in the cavopulmonary anastomosis by means of a modified Blalock-Taussig shunt: Is it a beneficial clinical option? In BIOSIGNALS 2013 - Proceedings of the International Conference on Bio-Inspired Systems and Signal Processing. 2013. p. 392-395
D'Avenio, Giuseppe ; Amodeo, Antonio ; Grigioni, Mauro. / Additional pulmonary blood flow in the cavopulmonary anastomosis by means of a modified Blalock-Taussig shunt : Is it a beneficial clinical option?. BIOSIGNALS 2013 - Proceedings of the International Conference on Bio-Inspired Systems and Signal Processing. 2013. pp. 392-395
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