Adenomyosis and its impact on women fertility

Elisabetta Garavaglia, Serafini Audrey, Inversetti Annalisa, Ferrari Stefano, Tandoi Iacopo, Corti Laura, Candiani Massimo

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Adenomyosis is a widespread disease affecting the reproductive period of women’s life. In the last ten years, different pathogenetic hypotheses have been proposed to explain the initiation and development of the disease. This article aims to present and discuss the most important pathophysiologic mechanisms underlying adenomyosis development in order to clarify the relationship between adenomyosis and infertility. A PubMed search was undertaken for English language literature using the MeSH terms ‘adenomyosis’, ‘infertility’, ‘treatment’, and ‘pathogenesis’. Although the exact etiology of adenomyosis is unknown, many theories have been proposed. We analysed the most important pathogenic theories expressed and evaluated the potential consequences on women fertility. A better comprehension of the adenomyosis pathogenesis has allowed realizing that adenomyosis may affect young women and may have a great impact on their fertility through different mechanisms. The understanding of these mechanisms helps to clarify the potential usefulness of current therapies.

Original languageEnglish
Pages (from-to)327-336
Number of pages10
JournalIranian Journal of Reproductive Medicine
Volume13
Issue number6
Publication statusPublished - Jun 1 2015

Fingerprint

Adenomyosis
Fertility
Infertility
PubMed
Reproduction
Language
Therapeutics

Keywords

  • Adenomyosis
  • Hyperestrogenism
  • Infertility
  • Pathogenesis
  • Treatment

ASJC Scopus subject areas

  • Reproductive Medicine
  • Obstetrics and Gynaecology

Cite this

Garavaglia, E., Audrey, S., Annalisa, I., Stefano, F., Iacopo, T., Laura, C., & Massimo, C. (2015). Adenomyosis and its impact on women fertility. Iranian Journal of Reproductive Medicine, 13(6), 327-336.

Adenomyosis and its impact on women fertility. / Garavaglia, Elisabetta; Audrey, Serafini; Annalisa, Inversetti; Stefano, Ferrari; Iacopo, Tandoi; Laura, Corti; Massimo, Candiani.

In: Iranian Journal of Reproductive Medicine, Vol. 13, No. 6, 01.06.2015, p. 327-336.

Research output: Contribution to journalArticle

Garavaglia, E, Audrey, S, Annalisa, I, Stefano, F, Iacopo, T, Laura, C & Massimo, C 2015, 'Adenomyosis and its impact on women fertility', Iranian Journal of Reproductive Medicine, vol. 13, no. 6, pp. 327-336.
Garavaglia E, Audrey S, Annalisa I, Stefano F, Iacopo T, Laura C et al. Adenomyosis and its impact on women fertility. Iranian Journal of Reproductive Medicine. 2015 Jun 1;13(6):327-336.
Garavaglia, Elisabetta ; Audrey, Serafini ; Annalisa, Inversetti ; Stefano, Ferrari ; Iacopo, Tandoi ; Laura, Corti ; Massimo, Candiani. / Adenomyosis and its impact on women fertility. In: Iranian Journal of Reproductive Medicine. 2015 ; Vol. 13, No. 6. pp. 327-336.
@article{57d5e585f09d42e0a9e54e1681cae44f,
title = "Adenomyosis and its impact on women fertility",
abstract = "Adenomyosis is a widespread disease affecting the reproductive period of women’s life. In the last ten years, different pathogenetic hypotheses have been proposed to explain the initiation and development of the disease. This article aims to present and discuss the most important pathophysiologic mechanisms underlying adenomyosis development in order to clarify the relationship between adenomyosis and infertility. A PubMed search was undertaken for English language literature using the MeSH terms ‘adenomyosis’, ‘infertility’, ‘treatment’, and ‘pathogenesis’. Although the exact etiology of adenomyosis is unknown, many theories have been proposed. We analysed the most important pathogenic theories expressed and evaluated the potential consequences on women fertility. A better comprehension of the adenomyosis pathogenesis has allowed realizing that adenomyosis may affect young women and may have a great impact on their fertility through different mechanisms. The understanding of these mechanisms helps to clarify the potential usefulness of current therapies.",
keywords = "Adenomyosis, Hyperestrogenism, Infertility, Pathogenesis, Treatment",
author = "Elisabetta Garavaglia and Serafini Audrey and Inversetti Annalisa and Ferrari Stefano and Tandoi Iacopo and Corti Laura and Candiani Massimo",
year = "2015",
month = "6",
day = "1",
language = "English",
volume = "13",
pages = "327--336",
journal = "Iranian Journal of Reproductive Medicine",
issn = "1680-6433",
publisher = "Research and Clinical Centre for Infertility",
number = "6",

}

TY - JOUR

T1 - Adenomyosis and its impact on women fertility

AU - Garavaglia, Elisabetta

AU - Audrey, Serafini

AU - Annalisa, Inversetti

AU - Stefano, Ferrari

AU - Iacopo, Tandoi

AU - Laura, Corti

AU - Massimo, Candiani

PY - 2015/6/1

Y1 - 2015/6/1

N2 - Adenomyosis is a widespread disease affecting the reproductive period of women’s life. In the last ten years, different pathogenetic hypotheses have been proposed to explain the initiation and development of the disease. This article aims to present and discuss the most important pathophysiologic mechanisms underlying adenomyosis development in order to clarify the relationship between adenomyosis and infertility. A PubMed search was undertaken for English language literature using the MeSH terms ‘adenomyosis’, ‘infertility’, ‘treatment’, and ‘pathogenesis’. Although the exact etiology of adenomyosis is unknown, many theories have been proposed. We analysed the most important pathogenic theories expressed and evaluated the potential consequences on women fertility. A better comprehension of the adenomyosis pathogenesis has allowed realizing that adenomyosis may affect young women and may have a great impact on their fertility through different mechanisms. The understanding of these mechanisms helps to clarify the potential usefulness of current therapies.

AB - Adenomyosis is a widespread disease affecting the reproductive period of women’s life. In the last ten years, different pathogenetic hypotheses have been proposed to explain the initiation and development of the disease. This article aims to present and discuss the most important pathophysiologic mechanisms underlying adenomyosis development in order to clarify the relationship between adenomyosis and infertility. A PubMed search was undertaken for English language literature using the MeSH terms ‘adenomyosis’, ‘infertility’, ‘treatment’, and ‘pathogenesis’. Although the exact etiology of adenomyosis is unknown, many theories have been proposed. We analysed the most important pathogenic theories expressed and evaluated the potential consequences on women fertility. A better comprehension of the adenomyosis pathogenesis has allowed realizing that adenomyosis may affect young women and may have a great impact on their fertility through different mechanisms. The understanding of these mechanisms helps to clarify the potential usefulness of current therapies.

KW - Adenomyosis

KW - Hyperestrogenism

KW - Infertility

KW - Pathogenesis

KW - Treatment

UR - http://www.scopus.com/inward/record.url?scp=84939201183&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84939201183&partnerID=8YFLogxK

M3 - Article

VL - 13

SP - 327

EP - 336

JO - Iranian Journal of Reproductive Medicine

JF - Iranian Journal of Reproductive Medicine

SN - 1680-6433

IS - 6

ER -