Adherence ability of Candida africana: A comparative study with Candida albicans and Candida dubliniensis

Orazio Romeo, Filomena De Leo, Giuseppe Criseo

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In this study, we compared the adherence ability to human Hela cells and biofilm formation of three closely related Candida yeast. In our experiments, Candida africana showed poor adhesion ability to human Hela cells and the absence of biofilm formation on polyvinyl chloride strips. Conversely, Candida albicans and Candida dubliniensis formed mature biofilms and stable attachment to Hela cells. To our knowledge, this is the first comparative study reporting data on biofilm formation and adherence to human Hela cells by C. africana.

Original languageEnglish
Issue number4
Publication statusPublished - Jul 2011



  • Candida africana
  • Candida albicans
  • Candida biofilm
  • Human Hela cells
  • HWP1 gene

ASJC Scopus subject areas

  • Dermatology
  • Infectious Diseases

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