Adherence to antibiotic treatment guidelines and outcomes in the hospitalized elderly with different types of pneumonia

Raffaella Rossio, Carlotta Franchi, Ilaria Ardoino, Codjo D. Djade, Mauro Tettamanti, Luca Pasina, Francesco Salerno, Alessandra Marengoni, Salvatore Corrao, Maura Marcucci, Flora Peyvandi, Elia M. Biganzoli, Alessandro Nobili, Pier Mannuccio Mannucci, Eleonora Sparacio, Stefania Alborghetti, Rosa Di Costanzo, Domenico Prisco, Elena Silvestri, Caterina CenciTommaso Barnini, Giuseppe Delitala, Stefano Carta, Sebastiana Atzori, Gianfranco Guarnieri, Michela Zanetti, Annalisa Spalluti, Maria Grazia Serra, Maria Antonietta Bleve, Massimo Vanoli, Giulia Grignani, Gianluca Casella, Laura Gasbarrone, Giorgio Maniscalco, Massimo Gunelli, Daniela Tirotta, Antonio Brucato, Silvia Ghidoni, Paola Di Corato, Mauro Bernardi, Silvia Li Bassi, Luca Santi, Giancarlo Agnelli, Alfonso Iorio, Emanuela Marchesini, Elmo Mannarino, Graziana Lupattelli, Pamela Rondelli, Francesco Paciullo, Fabrizio Fabris, Michela Carlon, Francesca Turatto, Maria Cristina Baroni, Marianna Zardo, Roberto Manfredini, Christian Molino, Marco Pala, Fabio Fabbian, Ranuccio Nuti, Roberto Valenti, Martina Ruvio, Silvia Cappelli, Giuseppe Paolisso, Maria Rosaria Rizzo, Maria Teresa Laieta, Teresa Salvatore, Ferdinando Carlo Sasso, Riccardo Utili, Emanuele Durante Mangoni, Daniela Pinto, Oliviero Olivieri, Anna Maria Stanzial, Renato Fellin, Stefano Volpato, Sioulis Fotini, Mario Barbagallo, Ligia Dominguez, Lidia Plances, Daniela D'Angelo, Giovanbattista Rini, Pasquale Mansueto, Ilenia Pepe, Giuseppe Licata, Luigi Calvo, Maria Valenti, Claudio Borghi, Enrico Strocchi, Elisa Rebecca Rinaldi, Marco Zoli, Elisa Fabbri, Donatella Magalotti, Alberto Auteri, Anna Laura Pasqui, Luca Puccetti, Franco Laghi Pasini, Pier Leopoldo Capecchi, Maurizio Bicchi, Carlo Sabbà, Francesco Saverio Vella, Alessandro Marseglia, Chiara Valentina Luglio, Giuseppe Palasciano, Maria Ester Modeo, Annamaria Aquilino, Pallante Raffaele, Stefania Pugliese, Caterina Capobianco, Alfredo Postiglione, Maria Rosaria Barbella, Francesco De Stefano, Luigi Fenoglio, Chiara Brignone, Christian Bracco, Alessia Giraudo, Giuseppe Musca, Olga Cuccurullo, Luigi Cricco, Alessandra Fiorentini, Maria Domenica Cappellini, Giovanna Fabio, Sonia Seghezzi, Margherita Migone De Amicis, Silvia Fargion, Paola Bonara, Mara Bulgheroni, Rosa Lombardi, Fabio Magrini, Ferdinando Massari, Tatiana Tonella, Alberto Tedeschi, Guido Moreo, Barbara Ferrari, Luisa Roncari, Valter Monzani, Valeria Savojardo, Christian Folli, Maria Magnini, Daniela Mari, Paolo Dionigi Rossi, Sarah Damanti, Silvia Prolo, Maria Sole Lilleri, Giuliana Micale, Mauro Podda, Carlo Selmi, Francesca Meda, Silvia Accordino, Alessio Conca, Valentina Monti, Gino Roberto Corazza, Emanuela Miceli, Marco Vincenzo Lenti, Donatella Padula, Carlo L. Balduini, Giampiera Bertolino, Stella Provini, Federica Quaglia, Giovanni Murialdo, Marta Bovio, Franco Dallegri, Luciano Ottonello, Alessandra Quercioli, Alessandra Barreca, Maria Beatrice Secchi, Davide Ghelfi, Wu Sheng Chin, Laura Carassale, Silvia Caporotundo, Luigi Anastasio, Lucia Sofia, Maria Carbone, Giancarlo Traisci, Lucrezia De Feudis, Silvia Di Carlo, Giovanni Davì, Maria Teresa Guagnano, Simona Sestili, Elisabetta Bergami, Emanuela Rizzioli, Carlo Cagnoni, Luca Bertone, Antonio Manucra, Alberto Buratti, Tiziana Tognin, Nicola Lucio Liberato, Giordano Bernasconi, Barbara Nardo, Giovanni Battista Bianchi, Giampiero Benetti, Michela Quagliolo, Giuseppe Riccardo Centenaro, Francesco Purrello, Antonino Di Pino, Salvatore Piro, Gerardo Mancuso, Daniela Calipari, Mosè Bartone, Francesco Gullo, Michele Cortellaro, Marina Magenta, Francesca Perego, Maria Rachele Meroni, Marco Cicardi, Antonio Gidaro Marina Magenta, Andrea Sacco, Antonio Bonelli, Gaetano Dentamaro, Renzo Rozzini, Lina Falanga, Alessandro Giordano, Paolo Cavallo Perin, Bartolomeo Lorenzati, Gabriella Gruden, Graziella Bruno, Giuseppe Montrucchio, Elisabetta Greco, Pietro Tizzani, Giacomo Fera, Maria Loreta Di Luca, Donatella Renna, Antonio Perciccante, Alessia Coralli, Rodolfo Tassara, Deborah Melis, Lara Rebella, Giorgio Menardo, Stefania Bottone, Elsa Sferrazzo, Claudio Ferri, Rinaldo Striuli, Rosa Scipioni, Raffaella Salmi, Piergiorgio Gaudenzi, Susanna Gamberini, Franco Ricci, Cosimo Morabito, Roberto Fava, Andrea Semplicini, Lucia Gottardo, Gianluigi Vendemiale, Gaetano Serviddio, Roberta Forlano, Luigi Bolondi, Leonardo Rasciti, Ilaria Serio, Cesare Masala, Antonio Mammarella, Valeria Raparelli, Filippo Rossi Fanelli, Massimo Delfino, Antonio Amoroso, Francesco Violi, Stefania Basili, Ludovica Perri, Pietro Serra, Vincenzo Fontana, Marco Falcone, Raffaele Landolfi, Antonio Grieco, Antonella Gallo, Giuseppe Zuccalà, Francesco Franceschi, Guido De Marco, Cordischi Chiara, Sabbatini Marta, Martino Bellusci, Donatella Setti, Filippo Pedrazzoli, Giuseppe Romanelli, Caterina Pirali, Claudia Amolini, Enrico Agabiti Rosei, Damiano Rizzoni, Luana Castoldi, Antonio Picardi, Umberto Vespasiani Gentilucci, Chiara Mazzarelli, Paolo Gallo, Luigina Guasti, Luana Castiglioni, Andrea Maresca, Alessandro Squizzato, Sara Contini, Marta Molaro, Giorgio Annoni, Maurizio Corsi, Sara Zazzetta, Marco Bertolotti, Chiara Mussi, Roberto Scotto, Maria Alice Ferri, Francesca Veltri, Franco Arturi, Elena Succurro, Giorgio Sesti, Umberto Gualtieri, Francesco Perticone, Angela Sciacqua, Michele Quero, Chiara Bagnato, Paola Loria, Maria Angela Becchi, Gianfranco Martucci, Alessandra Fantuzzi, Mauro Maurantonio, Roberto Corinaldesi, Roberto De Giorgio, Mauro Serra, Valentina Grasso, Eugenio Ruggeri, Lorenzo Mauro Carozza, Fabio Pignatti

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

Background: Few studies evaluated the clinical outcomes of Community Acquired Pneumonia (CAP), Hospital-Acquired Pneumonia (HAP) and Health Care-Associated Pneumonia (HCAP) in relation to the adherence of antibiotic treatment to the guidelines of the Infectious Diseases Society of America (IDSA) and the American Thoracic Society (ATS) in hospitalized elderly people (65 years or older). Methods: Data were obtained from REPOSI, a prospective registry held in 87 Italian internal medicine and geriatric wards. Patients with a diagnosis of pneumonia (ICD-9 480-487) or prescribed with an antibiotic for pneumonia as indication were selected. The empirical antibiotic regimen was defined to be adherent to guidelines if concordant with the treatment regimens recommended by IDSA/ATS for CAP, HAP, and HCAP. Outcomes were assessed by logistic regression models. Results: A diagnosis of pneumonia was made in 317 patients. Only 38.8% of them received an empirical antibiotic regimen that was adherent to guidelines. However, no significant association was found between adherence to guidelines and outcomes. Having HAP, older age, and higher CIRS severity index were the main factors associated with in-hospital mortality. Conclusions: The adherence to antibiotic treatment guidelines was poor, particularly for HAP and HCAP, suggesting the need for more adherence to the optimal management of antibiotics in the elderly with pneumonia.

Original languageEnglish
Pages (from-to)330-337
Number of pages8
JournalEuropean Journal of Internal Medicine
Volume26
Issue number5
DOIs
Publication statusPublished - Jun 1 2015

Fingerprint

Pneumonia
Guidelines
Anti-Bacterial Agents
Delivery of Health Care
Logistic Models
Guideline Adherence
International Classification of Diseases
Internal Medicine
Hospital Mortality
Geriatrics
Communicable Diseases
Registries
Thorax
Therapeutics

Keywords

  • Antibiotics
  • Elderly
  • Guidelines adherence
  • Mortality
  • Pneumonia
  • Re-hospitalization

ASJC Scopus subject areas

  • Internal Medicine
  • Medicine(all)

Cite this

Adherence to antibiotic treatment guidelines and outcomes in the hospitalized elderly with different types of pneumonia. / Rossio, Raffaella; Franchi, Carlotta; Ardoino, Ilaria; Djade, Codjo D.; Tettamanti, Mauro; Pasina, Luca; Salerno, Francesco; Marengoni, Alessandra; Corrao, Salvatore; Marcucci, Maura; Peyvandi, Flora; Biganzoli, Elia M.; Nobili, Alessandro; Mannucci, Pier Mannuccio; Sparacio, Eleonora; Alborghetti, Stefania; Di Costanzo, Rosa; Prisco, Domenico; Silvestri, Elena; Cenci, Caterina; Barnini, Tommaso; Delitala, Giuseppe; Carta, Stefano; Atzori, Sebastiana; Guarnieri, Gianfranco; Zanetti, Michela; Spalluti, Annalisa; Serra, Maria Grazia; Bleve, Maria Antonietta; Vanoli, Massimo; Grignani, Giulia; Casella, Gianluca; Gasbarrone, Laura; Maniscalco, Giorgio; Gunelli, Massimo; Tirotta, Daniela; Brucato, Antonio; Ghidoni, Silvia; Di Corato, Paola; Bernardi, Mauro; Li Bassi, Silvia; Santi, Luca; Agnelli, Giancarlo; Iorio, Alfonso; Marchesini, Emanuela; Mannarino, Elmo; Lupattelli, Graziana; Rondelli, Pamela; Paciullo, Francesco; Fabris, Fabrizio; Carlon, Michela; Turatto, Francesca; Baroni, Maria Cristina; Zardo, Marianna; Manfredini, Roberto; Molino, Christian; Pala, Marco; Fabbian, Fabio; Nuti, Ranuccio; Valenti, Roberto; Ruvio, Martina; Cappelli, Silvia; Paolisso, Giuseppe; Rizzo, Maria Rosaria; Laieta, Maria Teresa; Salvatore, Teresa; Sasso, Ferdinando Carlo; Utili, Riccardo; Mangoni, Emanuele Durante; Pinto, Daniela; Olivieri, Oliviero; Stanzial, Anna Maria; Fellin, Renato; Volpato, Stefano; Fotini, Sioulis; Barbagallo, Mario; Dominguez, Ligia; Plances, Lidia; D'Angelo, Daniela; Rini, Giovanbattista; Mansueto, Pasquale; Pepe, Ilenia; Licata, Giuseppe; Calvo, Luigi; Valenti, Maria; Borghi, Claudio; Strocchi, Enrico; Rinaldi, Elisa Rebecca; Zoli, Marco; Fabbri, Elisa; Magalotti, Donatella; Auteri, Alberto; Pasqui, Anna Laura; Puccetti, Luca; Pasini, Franco Laghi; Capecchi, Pier Leopoldo; Bicchi, Maurizio; Sabbà, Carlo; Vella, Francesco Saverio; Marseglia, Alessandro; Luglio, Chiara Valentina; Palasciano, Giuseppe; Modeo, Maria Ester; Aquilino, Annamaria; Raffaele, Pallante; Pugliese, Stefania; Capobianco, Caterina; Postiglione, Alfredo; Barbella, Maria Rosaria; De Stefano, Francesco; Fenoglio, Luigi; Brignone, Chiara; Bracco, Christian; Giraudo, Alessia; Musca, Giuseppe; Cuccurullo, Olga; Cricco, Luigi; Fiorentini, Alessandra; Cappellini, Maria Domenica; Fabio, Giovanna; Seghezzi, Sonia; De Amicis, Margherita Migone; Fargion, Silvia; Bonara, Paola; Bulgheroni, Mara; Lombardi, Rosa; Magrini, Fabio; Massari, Ferdinando; Tonella, Tatiana; Tedeschi, Alberto; Moreo, Guido; Ferrari, Barbara; Roncari, Luisa; Monzani, Valter; Savojardo, Valeria; Folli, Christian; Magnini, Maria; Mari, Daniela; Rossi, Paolo Dionigi; Damanti, Sarah; Prolo, Silvia; Lilleri, Maria Sole; Micale, Giuliana; Podda, Mauro; Selmi, Carlo; Meda, Francesca; Accordino, Silvia; Conca, Alessio; Monti, Valentina; Corazza, Gino Roberto; Miceli, Emanuela; Lenti, Marco Vincenzo; Padula, Donatella; Balduini, Carlo L.; Bertolino, Giampiera; Provini, Stella; Quaglia, Federica; Murialdo, Giovanni; Bovio, Marta; Dallegri, Franco; Ottonello, Luciano; Quercioli, Alessandra; Barreca, Alessandra; Secchi, Maria Beatrice; Ghelfi, Davide; Chin, Wu Sheng; Carassale, Laura; Caporotundo, Silvia; Anastasio, Luigi; Sofia, Lucia; Carbone, Maria; Traisci, Giancarlo; De Feudis, Lucrezia; Di Carlo, Silvia; Davì, Giovanni; Guagnano, Maria Teresa; Sestili, Simona; Bergami, Elisabetta; Rizzioli, Emanuela; Cagnoni, Carlo; Bertone, Luca; Manucra, Antonio; Buratti, Alberto; Tognin, Tiziana; Liberato, Nicola Lucio; Bernasconi, Giordano; Nardo, Barbara; Bianchi, Giovanni Battista; Benetti, Giampiero; Quagliolo, Michela; Centenaro, Giuseppe Riccardo; Purrello, Francesco; Di Pino, Antonino; Piro, Salvatore; Mancuso, Gerardo; Calipari, Daniela; Bartone, Mosè; Gullo, Francesco; Cortellaro, Michele; Magenta, Marina; Perego, Francesca; Meroni, Maria Rachele; Cicardi, Marco; Magenta, Antonio Gidaro Marina; Sacco, Andrea; Bonelli, Antonio; Dentamaro, Gaetano; Rozzini, Renzo; Falanga, Lina; Giordano, Alessandro; Perin, Paolo Cavallo; Lorenzati, Bartolomeo; Gruden, Gabriella; Bruno, Graziella; Montrucchio, Giuseppe; Greco, Elisabetta; Tizzani, Pietro; Fera, Giacomo; Di Luca, Maria Loreta; Renna, Donatella; Perciccante, Antonio; Coralli, Alessia; Tassara, Rodolfo; Melis, Deborah; Rebella, Lara; Menardo, Giorgio; Bottone, Stefania; Sferrazzo, Elsa; Ferri, Claudio; Striuli, Rinaldo; Scipioni, Rosa; Salmi, Raffaella; Gaudenzi, Piergiorgio; Gamberini, Susanna; Ricci, Franco; Morabito, Cosimo; Fava, Roberto; Semplicini, Andrea; Gottardo, Lucia; Vendemiale, Gianluigi; Serviddio, Gaetano; Forlano, Roberta; Bolondi, Luigi; Rasciti, Leonardo; Serio, Ilaria; Masala, Cesare; Mammarella, Antonio; Raparelli, Valeria; Fanelli, Filippo Rossi; Delfino, Massimo; Amoroso, Antonio; Violi, Francesco; Basili, Stefania; Perri, Ludovica; Serra, Pietro; Fontana, Vincenzo; Falcone, Marco; Landolfi, Raffaele; Grieco, Antonio; Gallo, Antonella; Zuccalà, Giuseppe; Franceschi, Francesco; De Marco, Guido; Chiara, Cordischi; Marta, Sabbatini; Bellusci, Martino; Setti, Donatella; Pedrazzoli, Filippo; Romanelli, Giuseppe; Pirali, Caterina; Amolini, Claudia; Rosei, Enrico Agabiti; Rizzoni, Damiano; Castoldi, Luana; Picardi, Antonio; Gentilucci, Umberto Vespasiani; Mazzarelli, Chiara; Gallo, Paolo; Guasti, Luigina; Castiglioni, Luana; Maresca, Andrea; Squizzato, Alessandro; Contini, Sara; Molaro, Marta; Annoni, Giorgio; Corsi, Maurizio; Zazzetta, Sara; Bertolotti, Marco; Mussi, Chiara; Scotto, Roberto; Ferri, Maria Alice; Veltri, Francesca; Arturi, Franco; Succurro, Elena; Sesti, Giorgio; Gualtieri, Umberto; Perticone, Francesco; Sciacqua, Angela; Quero, Michele; Bagnato, Chiara; Loria, Paola; Becchi, Maria Angela; Martucci, Gianfranco; Fantuzzi, Alessandra; Maurantonio, Mauro; Corinaldesi, Roberto; De Giorgio, Roberto; Serra, Mauro; Grasso, Valentina; Ruggeri, Eugenio; Carozza, Lorenzo Mauro; Pignatti, Fabio.

In: European Journal of Internal Medicine, Vol. 26, No. 5, 01.06.2015, p. 330-337.

Research output: Contribution to journalArticle

Rossio, R, Franchi, C, Ardoino, I, Djade, CD, Tettamanti, M, Pasina, L, Salerno, F, Marengoni, A, Corrao, S, Marcucci, M, Peyvandi, F, Biganzoli, EM, Nobili, A, Mannucci, PM, Sparacio, E, Alborghetti, S, Di Costanzo, R, Prisco, D, Silvestri, E, Cenci, C, Barnini, T, Delitala, G, Carta, S, Atzori, S, Guarnieri, G, Zanetti, M, Spalluti, A, Serra, MG, Bleve, MA, Vanoli, M, Grignani, G, Casella, G, Gasbarrone, L, Maniscalco, G, Gunelli, M, Tirotta, D, Brucato, A, Ghidoni, S, Di Corato, P, Bernardi, M, Li Bassi, S, Santi, L, Agnelli, G, Iorio, A, Marchesini, E, Mannarino, E, Lupattelli, G, Rondelli, P, Paciullo, F, Fabris, F, Carlon, M, Turatto, F, Baroni, MC, Zardo, M, Manfredini, R, Molino, C, Pala, M, Fabbian, F, Nuti, R, Valenti, R, Ruvio, M, Cappelli, S, Paolisso, G, Rizzo, MR, Laieta, MT, Salvatore, T, Sasso, FC, Utili, R, Mangoni, ED, Pinto, D, Olivieri, O, Stanzial, AM, Fellin, R, Volpato, S, Fotini, S, Barbagallo, M, Dominguez, L, Plances, L, D'Angelo, D, Rini, G, Mansueto, P, Pepe, I, Licata, G, Calvo, L, Valenti, M, Borghi, C, Strocchi, E, Rinaldi, ER, Zoli, M, Fabbri, E, Magalotti, D, Auteri, A, Pasqui, AL, Puccetti, L, Pasini, FL, Capecchi, PL, Bicchi, M, Sabbà, C, Vella, FS, Marseglia, A, Luglio, CV, Palasciano, G, Modeo, ME, Aquilino, A, Raffaele, P, Pugliese, S, Capobianco, C, Postiglione, A, Barbella, MR, De Stefano, F, Fenoglio, L, Brignone, C, Bracco, C, Giraudo, A, Musca, G, Cuccurullo, O, Cricco, L, Fiorentini, A, Cappellini, MD, Fabio, G, Seghezzi, S, De Amicis, MM, Fargion, S, Bonara, P, Bulgheroni, M, Lombardi, R, Magrini, F, Massari, F, Tonella, T, Tedeschi, A, Moreo, G, Ferrari, B, Roncari, L, Monzani, V, Savojardo, V, Folli, C, Magnini, M, Mari, D, Rossi, PD, Damanti, S, Prolo, S, Lilleri, MS, Micale, G, Podda, M, Selmi, C, Meda, F, Accordino, S, Conca, A, Monti, V, Corazza, GR, Miceli, E, Lenti, MV, Padula, D, Balduini, CL, Bertolino, G, Provini, S, Quaglia, F, Murialdo, G, Bovio, M, Dallegri, F, Ottonello, L, Quercioli, A, Barreca, A, Secchi, MB, Ghelfi, D, Chin, WS, Carassale, L, Caporotundo, S, Anastasio, L, Sofia, L, Carbone, M, Traisci, G, De Feudis, L, Di Carlo, S, Davì, G, Guagnano, MT, Sestili, S, Bergami, E, Rizzioli, E, Cagnoni, C, Bertone, L, Manucra, A, Buratti, A, Tognin, T, Liberato, NL, Bernasconi, G, Nardo, B, Bianchi, GB, Benetti, G, Quagliolo, M, Centenaro, GR, Purrello, F, Di Pino, A, Piro, S, Mancuso, G, Calipari, D, Bartone, M, Gullo, F, Cortellaro, M, Magenta, M, Perego, F, Meroni, MR, Cicardi, M, Magenta, AGM, Sacco, A, Bonelli, A, Dentamaro, G, Rozzini, R, Falanga, L, Giordano, A, Perin, PC, Lorenzati, B, Gruden, G, Bruno, G, Montrucchio, G, Greco, E, Tizzani, P, Fera, G, Di Luca, ML, Renna, D, Perciccante, A, Coralli, A, Tassara, R, Melis, D, Rebella, L, Menardo, G, Bottone, S, Sferrazzo, E, Ferri, C, Striuli, R, Scipioni, R, Salmi, R, Gaudenzi, P, Gamberini, S, Ricci, F, Morabito, C, Fava, R, Semplicini, A, Gottardo, L, Vendemiale, G, Serviddio, G, Forlano, R, Bolondi, L, Rasciti, L, Serio, I, Masala, C, Mammarella, A, Raparelli, V, Fanelli, FR, Delfino, M, Amoroso, A, Violi, F, Basili, S, Perri, L, Serra, P, Fontana, V, Falcone, M, Landolfi, R, Grieco, A, Gallo, A, Zuccalà, G, Franceschi, F, De Marco, G, Chiara, C, Marta, S, Bellusci, M, Setti, D, Pedrazzoli, F, Romanelli, G, Pirali, C, Amolini, C, Rosei, EA, Rizzoni, D, Castoldi, L, Picardi, A, Gentilucci, UV, Mazzarelli, C, Gallo, P, Guasti, L, Castiglioni, L, Maresca, A, Squizzato, A, Contini, S, Molaro, M, Annoni, G, Corsi, M, Zazzetta, S, Bertolotti, M, Mussi, C, Scotto, R, Ferri, MA, Veltri, F, Arturi, F, Succurro, E, Sesti, G, Gualtieri, U, Perticone, F, Sciacqua, A, Quero, M, Bagnato, C, Loria, P, Becchi, MA, Martucci, G, Fantuzzi, A, Maurantonio, M, Corinaldesi, R, De Giorgio, R, Serra, M, Grasso, V, Ruggeri, E, Carozza, LM & Pignatti, F 2015, 'Adherence to antibiotic treatment guidelines and outcomes in the hospitalized elderly with different types of pneumonia', European Journal of Internal Medicine, vol. 26, no. 5, pp. 330-337. https://doi.org/10.1016/j.ejim.2015.04.002
Rossio, Raffaella ; Franchi, Carlotta ; Ardoino, Ilaria ; Djade, Codjo D. ; Tettamanti, Mauro ; Pasina, Luca ; Salerno, Francesco ; Marengoni, Alessandra ; Corrao, Salvatore ; Marcucci, Maura ; Peyvandi, Flora ; Biganzoli, Elia M. ; Nobili, Alessandro ; Mannucci, Pier Mannuccio ; Sparacio, Eleonora ; Alborghetti, Stefania ; Di Costanzo, Rosa ; Prisco, Domenico ; Silvestri, Elena ; Cenci, Caterina ; Barnini, Tommaso ; Delitala, Giuseppe ; Carta, Stefano ; Atzori, Sebastiana ; Guarnieri, Gianfranco ; Zanetti, Michela ; Spalluti, Annalisa ; Serra, Maria Grazia ; Bleve, Maria Antonietta ; Vanoli, Massimo ; Grignani, Giulia ; Casella, Gianluca ; Gasbarrone, Laura ; Maniscalco, Giorgio ; Gunelli, Massimo ; Tirotta, Daniela ; Brucato, Antonio ; Ghidoni, Silvia ; Di Corato, Paola ; Bernardi, Mauro ; Li Bassi, Silvia ; Santi, Luca ; Agnelli, Giancarlo ; Iorio, Alfonso ; Marchesini, Emanuela ; Mannarino, Elmo ; Lupattelli, Graziana ; Rondelli, Pamela ; Paciullo, Francesco ; Fabris, Fabrizio ; Carlon, Michela ; Turatto, Francesca ; Baroni, Maria Cristina ; Zardo, Marianna ; Manfredini, Roberto ; Molino, Christian ; Pala, Marco ; Fabbian, Fabio ; Nuti, Ranuccio ; Valenti, Roberto ; Ruvio, Martina ; Cappelli, Silvia ; Paolisso, Giuseppe ; Rizzo, Maria Rosaria ; Laieta, Maria Teresa ; Salvatore, Teresa ; Sasso, Ferdinando Carlo ; Utili, Riccardo ; Mangoni, Emanuele Durante ; Pinto, Daniela ; Olivieri, Oliviero ; Stanzial, Anna Maria ; Fellin, Renato ; Volpato, Stefano ; Fotini, Sioulis ; Barbagallo, Mario ; Dominguez, Ligia ; Plances, Lidia ; D'Angelo, Daniela ; Rini, Giovanbattista ; Mansueto, Pasquale ; Pepe, Ilenia ; Licata, Giuseppe ; Calvo, Luigi ; Valenti, Maria ; Borghi, Claudio ; Strocchi, Enrico ; Rinaldi, Elisa Rebecca ; Zoli, Marco ; Fabbri, Elisa ; Magalotti, Donatella ; Auteri, Alberto ; Pasqui, Anna Laura ; Puccetti, Luca ; Pasini, Franco Laghi ; Capecchi, Pier Leopoldo ; Bicchi, Maurizio ; Sabbà, Carlo ; Vella, Francesco Saverio ; Marseglia, Alessandro ; Luglio, Chiara Valentina ; Palasciano, Giuseppe ; Modeo, Maria Ester ; Aquilino, Annamaria ; Raffaele, Pallante ; Pugliese, Stefania ; Capobianco, Caterina ; Postiglione, Alfredo ; Barbella, Maria Rosaria ; De Stefano, Francesco ; Fenoglio, Luigi ; Brignone, Chiara ; Bracco, Christian ; Giraudo, Alessia ; Musca, Giuseppe ; Cuccurullo, Olga ; Cricco, Luigi ; Fiorentini, Alessandra ; Cappellini, Maria Domenica ; Fabio, Giovanna ; Seghezzi, Sonia ; De Amicis, Margherita Migone ; Fargion, Silvia ; Bonara, Paola ; Bulgheroni, Mara ; Lombardi, Rosa ; Magrini, Fabio ; Massari, Ferdinando ; Tonella, Tatiana ; Tedeschi, Alberto ; Moreo, Guido ; Ferrari, Barbara ; Roncari, Luisa ; Monzani, Valter ; Savojardo, Valeria ; Folli, Christian ; Magnini, Maria ; Mari, Daniela ; Rossi, Paolo Dionigi ; Damanti, Sarah ; Prolo, Silvia ; Lilleri, Maria Sole ; Micale, Giuliana ; Podda, Mauro ; Selmi, Carlo ; Meda, Francesca ; Accordino, Silvia ; Conca, Alessio ; Monti, Valentina ; Corazza, Gino Roberto ; Miceli, Emanuela ; Lenti, Marco Vincenzo ; Padula, Donatella ; Balduini, Carlo L. ; Bertolino, Giampiera ; Provini, Stella ; Quaglia, Federica ; Murialdo, Giovanni ; Bovio, Marta ; Dallegri, Franco ; Ottonello, Luciano ; Quercioli, Alessandra ; Barreca, Alessandra ; Secchi, Maria Beatrice ; Ghelfi, Davide ; Chin, Wu Sheng ; Carassale, Laura ; Caporotundo, Silvia ; Anastasio, Luigi ; Sofia, Lucia ; Carbone, Maria ; Traisci, Giancarlo ; De Feudis, Lucrezia ; Di Carlo, Silvia ; Davì, Giovanni ; Guagnano, Maria Teresa ; Sestili, Simona ; Bergami, Elisabetta ; Rizzioli, Emanuela ; Cagnoni, Carlo ; Bertone, Luca ; Manucra, Antonio ; Buratti, Alberto ; Tognin, Tiziana ; Liberato, Nicola Lucio ; Bernasconi, Giordano ; Nardo, Barbara ; Bianchi, Giovanni Battista ; Benetti, Giampiero ; Quagliolo, Michela ; Centenaro, Giuseppe Riccardo ; Purrello, Francesco ; Di Pino, Antonino ; Piro, Salvatore ; Mancuso, Gerardo ; Calipari, Daniela ; Bartone, Mosè ; Gullo, Francesco ; Cortellaro, Michele ; Magenta, Marina ; Perego, Francesca ; Meroni, Maria Rachele ; Cicardi, Marco ; Magenta, Antonio Gidaro Marina ; Sacco, Andrea ; Bonelli, Antonio ; Dentamaro, Gaetano ; Rozzini, Renzo ; Falanga, Lina ; Giordano, Alessandro ; Perin, Paolo Cavallo ; Lorenzati, Bartolomeo ; Gruden, Gabriella ; Bruno, Graziella ; Montrucchio, Giuseppe ; Greco, Elisabetta ; Tizzani, Pietro ; Fera, Giacomo ; Di Luca, Maria Loreta ; Renna, Donatella ; Perciccante, Antonio ; Coralli, Alessia ; Tassara, Rodolfo ; Melis, Deborah ; Rebella, Lara ; Menardo, Giorgio ; Bottone, Stefania ; Sferrazzo, Elsa ; Ferri, Claudio ; Striuli, Rinaldo ; Scipioni, Rosa ; Salmi, Raffaella ; Gaudenzi, Piergiorgio ; Gamberini, Susanna ; Ricci, Franco ; Morabito, Cosimo ; Fava, Roberto ; Semplicini, Andrea ; Gottardo, Lucia ; Vendemiale, Gianluigi ; Serviddio, Gaetano ; Forlano, Roberta ; Bolondi, Luigi ; Rasciti, Leonardo ; Serio, Ilaria ; Masala, Cesare ; Mammarella, Antonio ; Raparelli, Valeria ; Fanelli, Filippo Rossi ; Delfino, Massimo ; Amoroso, Antonio ; Violi, Francesco ; Basili, Stefania ; Perri, Ludovica ; Serra, Pietro ; Fontana, Vincenzo ; Falcone, Marco ; Landolfi, Raffaele ; Grieco, Antonio ; Gallo, Antonella ; Zuccalà, Giuseppe ; Franceschi, Francesco ; De Marco, Guido ; Chiara, Cordischi ; Marta, Sabbatini ; Bellusci, Martino ; Setti, Donatella ; Pedrazzoli, Filippo ; Romanelli, Giuseppe ; Pirali, Caterina ; Amolini, Claudia ; Rosei, Enrico Agabiti ; Rizzoni, Damiano ; Castoldi, Luana ; Picardi, Antonio ; Gentilucci, Umberto Vespasiani ; Mazzarelli, Chiara ; Gallo, Paolo ; Guasti, Luigina ; Castiglioni, Luana ; Maresca, Andrea ; Squizzato, Alessandro ; Contini, Sara ; Molaro, Marta ; Annoni, Giorgio ; Corsi, Maurizio ; Zazzetta, Sara ; Bertolotti, Marco ; Mussi, Chiara ; Scotto, Roberto ; Ferri, Maria Alice ; Veltri, Francesca ; Arturi, Franco ; Succurro, Elena ; Sesti, Giorgio ; Gualtieri, Umberto ; Perticone, Francesco ; Sciacqua, Angela ; Quero, Michele ; Bagnato, Chiara ; Loria, Paola ; Becchi, Maria Angela ; Martucci, Gianfranco ; Fantuzzi, Alessandra ; Maurantonio, Mauro ; Corinaldesi, Roberto ; De Giorgio, Roberto ; Serra, Mauro ; Grasso, Valentina ; Ruggeri, Eugenio ; Carozza, Lorenzo Mauro ; Pignatti, Fabio. / Adherence to antibiotic treatment guidelines and outcomes in the hospitalized elderly with different types of pneumonia. In: European Journal of Internal Medicine. 2015 ; Vol. 26, No. 5. pp. 330-337.
@article{09f8bbe53bc3458887417f170a2ed364,
title = "Adherence to antibiotic treatment guidelines and outcomes in the hospitalized elderly with different types of pneumonia",
abstract = "Background: Few studies evaluated the clinical outcomes of Community Acquired Pneumonia (CAP), Hospital-Acquired Pneumonia (HAP) and Health Care-Associated Pneumonia (HCAP) in relation to the adherence of antibiotic treatment to the guidelines of the Infectious Diseases Society of America (IDSA) and the American Thoracic Society (ATS) in hospitalized elderly people (65 years or older). Methods: Data were obtained from REPOSI, a prospective registry held in 87 Italian internal medicine and geriatric wards. Patients with a diagnosis of pneumonia (ICD-9 480-487) or prescribed with an antibiotic for pneumonia as indication were selected. The empirical antibiotic regimen was defined to be adherent to guidelines if concordant with the treatment regimens recommended by IDSA/ATS for CAP, HAP, and HCAP. Outcomes were assessed by logistic regression models. Results: A diagnosis of pneumonia was made in 317 patients. Only 38.8{\%} of them received an empirical antibiotic regimen that was adherent to guidelines. However, no significant association was found between adherence to guidelines and outcomes. Having HAP, older age, and higher CIRS severity index were the main factors associated with in-hospital mortality. Conclusions: The adherence to antibiotic treatment guidelines was poor, particularly for HAP and HCAP, suggesting the need for more adherence to the optimal management of antibiotics in the elderly with pneumonia.",
keywords = "Antibiotics, Elderly, Guidelines adherence, Mortality, Pneumonia, Re-hospitalization",
author = "Raffaella Rossio and Carlotta Franchi and Ilaria Ardoino and Djade, {Codjo D.} and Mauro Tettamanti and Luca Pasina and Francesco Salerno and Alessandra Marengoni and Salvatore Corrao and Maura Marcucci and Flora Peyvandi and Biganzoli, {Elia M.} and Alessandro Nobili and Mannucci, {Pier Mannuccio} and Eleonora Sparacio and Stefania Alborghetti and {Di Costanzo}, Rosa and Domenico Prisco and Elena Silvestri and Caterina Cenci and Tommaso Barnini and Giuseppe Delitala and Stefano Carta and Sebastiana Atzori and Gianfranco Guarnieri and Michela Zanetti and Annalisa Spalluti and Serra, {Maria Grazia} and Bleve, {Maria Antonietta} and Massimo Vanoli and Giulia Grignani and Gianluca Casella and Laura Gasbarrone and Giorgio Maniscalco and Massimo Gunelli and Daniela Tirotta and Antonio Brucato and Silvia Ghidoni and {Di Corato}, Paola and Mauro Bernardi and {Li Bassi}, Silvia and Luca Santi and Giancarlo Agnelli and Alfonso Iorio and Emanuela Marchesini and Elmo Mannarino and Graziana Lupattelli and Pamela Rondelli and Francesco Paciullo and Fabrizio Fabris and Michela Carlon and Francesca Turatto and Baroni, {Maria Cristina} and Marianna Zardo and Roberto Manfredini and Christian Molino and Marco Pala and Fabio Fabbian and Ranuccio Nuti and Roberto Valenti and Martina Ruvio and Silvia Cappelli and Giuseppe Paolisso and Rizzo, {Maria Rosaria} and Laieta, {Maria Teresa} and Teresa Salvatore and Sasso, {Ferdinando Carlo} and Riccardo Utili and Mangoni, {Emanuele Durante} and Daniela Pinto and Oliviero Olivieri and Stanzial, {Anna Maria} and Renato Fellin and Stefano Volpato and Sioulis Fotini and Mario Barbagallo and Ligia Dominguez and Lidia Plances and Daniela D'Angelo and Giovanbattista Rini and Pasquale Mansueto and Ilenia Pepe and Giuseppe Licata and Luigi Calvo and Maria Valenti and Claudio Borghi and Enrico Strocchi and Rinaldi, {Elisa Rebecca} and Marco Zoli and Elisa Fabbri and Donatella Magalotti and Alberto Auteri and Pasqui, {Anna Laura} and Luca Puccetti and Pasini, {Franco Laghi} and Capecchi, {Pier Leopoldo} and Maurizio Bicchi and Carlo Sabb{\`a} and Vella, {Francesco Saverio} and Alessandro Marseglia and Luglio, {Chiara Valentina} and Giuseppe Palasciano and Modeo, {Maria Ester} and Annamaria Aquilino and Pallante Raffaele and Stefania Pugliese and Caterina Capobianco and Alfredo Postiglione and Barbella, {Maria Rosaria} and {De Stefano}, Francesco and Luigi Fenoglio and Chiara Brignone and Christian Bracco and Alessia Giraudo and Giuseppe Musca and Olga Cuccurullo and Luigi Cricco and Alessandra Fiorentini and Cappellini, {Maria Domenica} and Giovanna Fabio and Sonia Seghezzi and {De Amicis}, {Margherita Migone} and Silvia Fargion and Paola Bonara and Mara Bulgheroni and Rosa Lombardi and Fabio Magrini and Ferdinando Massari and Tatiana Tonella and Alberto Tedeschi and Guido Moreo and Barbara Ferrari and Luisa Roncari and Valter Monzani and Valeria Savojardo and Christian Folli and Maria Magnini and Daniela Mari and Rossi, {Paolo Dionigi} and Sarah Damanti and Silvia Prolo and Lilleri, {Maria Sole} and Giuliana Micale and Mauro Podda and Carlo Selmi and Francesca Meda and Silvia Accordino and Alessio Conca and Valentina Monti and Corazza, {Gino Roberto} and Emanuela Miceli and Lenti, {Marco Vincenzo} and Donatella Padula and Balduini, {Carlo L.} and Giampiera Bertolino and Stella Provini and Federica Quaglia and Giovanni Murialdo and Marta Bovio and Franco Dallegri and Luciano Ottonello and Alessandra Quercioli and Alessandra Barreca and Secchi, {Maria Beatrice} and Davide Ghelfi and Chin, {Wu Sheng} and Laura Carassale and Silvia Caporotundo and Luigi Anastasio and Lucia Sofia and Maria Carbone and Giancarlo Traisci and {De Feudis}, Lucrezia and {Di Carlo}, Silvia and Giovanni Dav{\`i} and Guagnano, {Maria Teresa} and Simona Sestili and Elisabetta Bergami and Emanuela Rizzioli and Carlo Cagnoni and Luca Bertone and Antonio Manucra and Alberto Buratti and Tiziana Tognin and Liberato, {Nicola Lucio} and Giordano Bernasconi and Barbara Nardo and Bianchi, {Giovanni Battista} and Giampiero Benetti and Michela Quagliolo and Centenaro, {Giuseppe Riccardo} and Francesco Purrello and {Di Pino}, Antonino and Salvatore Piro and Gerardo Mancuso and Daniela Calipari and Mos{\`e} Bartone and Francesco Gullo and Michele Cortellaro and Marina Magenta and Francesca Perego and Meroni, {Maria Rachele} and Marco Cicardi and Magenta, {Antonio Gidaro Marina} and Andrea Sacco and Antonio Bonelli and Gaetano Dentamaro and Renzo Rozzini and Lina Falanga and Alessandro Giordano and Perin, {Paolo Cavallo} and Bartolomeo Lorenzati and Gabriella Gruden and Graziella Bruno and Giuseppe Montrucchio and Elisabetta Greco and Pietro Tizzani and Giacomo Fera and {Di Luca}, {Maria Loreta} and Donatella Renna and Antonio Perciccante and Alessia Coralli and Rodolfo Tassara and Deborah Melis and Lara Rebella and Giorgio Menardo and Stefania Bottone and Elsa Sferrazzo and Claudio Ferri and Rinaldo Striuli and Rosa Scipioni and Raffaella Salmi and Piergiorgio Gaudenzi and Susanna Gamberini and Franco Ricci and Cosimo Morabito and Roberto Fava and Andrea Semplicini and Lucia Gottardo and Gianluigi Vendemiale and Gaetano Serviddio and Roberta Forlano and Luigi Bolondi and Leonardo Rasciti and Ilaria Serio and Cesare Masala and Antonio Mammarella and Valeria Raparelli and Fanelli, {Filippo Rossi} and Massimo Delfino and Antonio Amoroso and Francesco Violi and Stefania Basili and Ludovica Perri and Pietro Serra and Vincenzo Fontana and Marco Falcone and Raffaele Landolfi and Antonio Grieco and Antonella Gallo and Giuseppe Zuccal{\`a} and Francesco Franceschi and {De Marco}, Guido and Cordischi Chiara and Sabbatini Marta and Martino Bellusci and Donatella Setti and Filippo Pedrazzoli and Giuseppe Romanelli and Caterina Pirali and Claudia Amolini and Rosei, {Enrico Agabiti} and Damiano Rizzoni and Luana Castoldi and Antonio Picardi and Gentilucci, {Umberto Vespasiani} and Chiara Mazzarelli and Paolo Gallo and Luigina Guasti and Luana Castiglioni and Andrea Maresca and Alessandro Squizzato and Sara Contini and Marta Molaro and Giorgio Annoni and Maurizio Corsi and Sara Zazzetta and Marco Bertolotti and Chiara Mussi and Roberto Scotto and Ferri, {Maria Alice} and Francesca Veltri and Franco Arturi and Elena Succurro and Giorgio Sesti and Umberto Gualtieri and Francesco Perticone and Angela Sciacqua and Michele Quero and Chiara Bagnato and Paola Loria and Becchi, {Maria Angela} and Gianfranco Martucci and Alessandra Fantuzzi and Mauro Maurantonio and Roberto Corinaldesi and {De Giorgio}, Roberto and Mauro Serra and Valentina Grasso and Eugenio Ruggeri and Carozza, {Lorenzo Mauro} and Fabio Pignatti",
year = "2015",
month = "6",
day = "1",
doi = "10.1016/j.ejim.2015.04.002",
language = "English",
volume = "26",
pages = "330--337",
journal = "European Journal of Internal Medicine",
issn = "0953-6205",
publisher = "Elsevier B.V.",
number = "5",

}

TY - JOUR

T1 - Adherence to antibiotic treatment guidelines and outcomes in the hospitalized elderly with different types of pneumonia

AU - Rossio, Raffaella

AU - Franchi, Carlotta

AU - Ardoino, Ilaria

AU - Djade, Codjo D.

AU - Tettamanti, Mauro

AU - Pasina, Luca

AU - Salerno, Francesco

AU - Marengoni, Alessandra

AU - Corrao, Salvatore

AU - Marcucci, Maura

AU - Peyvandi, Flora

AU - Biganzoli, Elia M.

AU - Nobili, Alessandro

AU - Mannucci, Pier Mannuccio

AU - Sparacio, Eleonora

AU - Alborghetti, Stefania

AU - Di Costanzo, Rosa

AU - Prisco, Domenico

AU - Silvestri, Elena

AU - Cenci, Caterina

AU - Barnini, Tommaso

AU - Delitala, Giuseppe

AU - Carta, Stefano

AU - Atzori, Sebastiana

AU - Guarnieri, Gianfranco

AU - Zanetti, Michela

AU - Spalluti, Annalisa

AU - Serra, Maria Grazia

AU - Bleve, Maria Antonietta

AU - Vanoli, Massimo

AU - Grignani, Giulia

AU - Casella, Gianluca

AU - Gasbarrone, Laura

AU - Maniscalco, Giorgio

AU - Gunelli, Massimo

AU - Tirotta, Daniela

AU - Brucato, Antonio

AU - Ghidoni, Silvia

AU - Di Corato, Paola

AU - Bernardi, Mauro

AU - Li Bassi, Silvia

AU - Santi, Luca

AU - Agnelli, Giancarlo

AU - Iorio, Alfonso

AU - Marchesini, Emanuela

AU - Mannarino, Elmo

AU - Lupattelli, Graziana

AU - Rondelli, Pamela

AU - Paciullo, Francesco

AU - Fabris, Fabrizio

AU - Carlon, Michela

AU - Turatto, Francesca

AU - Baroni, Maria Cristina

AU - Zardo, Marianna

AU - Manfredini, Roberto

AU - Molino, Christian

AU - Pala, Marco

AU - Fabbian, Fabio

AU - Nuti, Ranuccio

AU - Valenti, Roberto

AU - Ruvio, Martina

AU - Cappelli, Silvia

AU - Paolisso, Giuseppe

AU - Rizzo, Maria Rosaria

AU - Laieta, Maria Teresa

AU - Salvatore, Teresa

AU - Sasso, Ferdinando Carlo

AU - Utili, Riccardo

AU - Mangoni, Emanuele Durante

AU - Pinto, Daniela

AU - Olivieri, Oliviero

AU - Stanzial, Anna Maria

AU - Fellin, Renato

AU - Volpato, Stefano

AU - Fotini, Sioulis

AU - Barbagallo, Mario

AU - Dominguez, Ligia

AU - Plances, Lidia

AU - D'Angelo, Daniela

AU - Rini, Giovanbattista

AU - Mansueto, Pasquale

AU - Pepe, Ilenia

AU - Licata, Giuseppe

AU - Calvo, Luigi

AU - Valenti, Maria

AU - Borghi, Claudio

AU - Strocchi, Enrico

AU - Rinaldi, Elisa Rebecca

AU - Zoli, Marco

AU - Fabbri, Elisa

AU - Magalotti, Donatella

AU - Auteri, Alberto

AU - Pasqui, Anna Laura

AU - Puccetti, Luca

AU - Pasini, Franco Laghi

AU - Capecchi, Pier Leopoldo

AU - Bicchi, Maurizio

AU - Sabbà, Carlo

AU - Vella, Francesco Saverio

AU - Marseglia, Alessandro

AU - Luglio, Chiara Valentina

AU - Palasciano, Giuseppe

AU - Modeo, Maria Ester

AU - Aquilino, Annamaria

AU - Raffaele, Pallante

AU - Pugliese, Stefania

AU - Capobianco, Caterina

AU - Postiglione, Alfredo

AU - Barbella, Maria Rosaria

AU - De Stefano, Francesco

AU - Fenoglio, Luigi

AU - Brignone, Chiara

AU - Bracco, Christian

AU - Giraudo, Alessia

AU - Musca, Giuseppe

AU - Cuccurullo, Olga

AU - Cricco, Luigi

AU - Fiorentini, Alessandra

AU - Cappellini, Maria Domenica

AU - Fabio, Giovanna

AU - Seghezzi, Sonia

AU - De Amicis, Margherita Migone

AU - Fargion, Silvia

AU - Bonara, Paola

AU - Bulgheroni, Mara

AU - Lombardi, Rosa

AU - Magrini, Fabio

AU - Massari, Ferdinando

AU - Tonella, Tatiana

AU - Tedeschi, Alberto

AU - Moreo, Guido

AU - Ferrari, Barbara

AU - Roncari, Luisa

AU - Monzani, Valter

AU - Savojardo, Valeria

AU - Folli, Christian

AU - Magnini, Maria

AU - Mari, Daniela

AU - Rossi, Paolo Dionigi

AU - Damanti, Sarah

AU - Prolo, Silvia

AU - Lilleri, Maria Sole

AU - Micale, Giuliana

AU - Podda, Mauro

AU - Selmi, Carlo

AU - Meda, Francesca

AU - Accordino, Silvia

AU - Conca, Alessio

AU - Monti, Valentina

AU - Corazza, Gino Roberto

AU - Miceli, Emanuela

AU - Lenti, Marco Vincenzo

AU - Padula, Donatella

AU - Balduini, Carlo L.

AU - Bertolino, Giampiera

AU - Provini, Stella

AU - Quaglia, Federica

AU - Murialdo, Giovanni

AU - Bovio, Marta

AU - Dallegri, Franco

AU - Ottonello, Luciano

AU - Quercioli, Alessandra

AU - Barreca, Alessandra

AU - Secchi, Maria Beatrice

AU - Ghelfi, Davide

AU - Chin, Wu Sheng

AU - Carassale, Laura

AU - Caporotundo, Silvia

AU - Anastasio, Luigi

AU - Sofia, Lucia

AU - Carbone, Maria

AU - Traisci, Giancarlo

AU - De Feudis, Lucrezia

AU - Di Carlo, Silvia

AU - Davì, Giovanni

AU - Guagnano, Maria Teresa

AU - Sestili, Simona

AU - Bergami, Elisabetta

AU - Rizzioli, Emanuela

AU - Cagnoni, Carlo

AU - Bertone, Luca

AU - Manucra, Antonio

AU - Buratti, Alberto

AU - Tognin, Tiziana

AU - Liberato, Nicola Lucio

AU - Bernasconi, Giordano

AU - Nardo, Barbara

AU - Bianchi, Giovanni Battista

AU - Benetti, Giampiero

AU - Quagliolo, Michela

AU - Centenaro, Giuseppe Riccardo

AU - Purrello, Francesco

AU - Di Pino, Antonino

AU - Piro, Salvatore

AU - Mancuso, Gerardo

AU - Calipari, Daniela

AU - Bartone, Mosè

AU - Gullo, Francesco

AU - Cortellaro, Michele

AU - Magenta, Marina

AU - Perego, Francesca

AU - Meroni, Maria Rachele

AU - Cicardi, Marco

AU - Magenta, Antonio Gidaro Marina

AU - Sacco, Andrea

AU - Bonelli, Antonio

AU - Dentamaro, Gaetano

AU - Rozzini, Renzo

AU - Falanga, Lina

AU - Giordano, Alessandro

AU - Perin, Paolo Cavallo

AU - Lorenzati, Bartolomeo

AU - Gruden, Gabriella

AU - Bruno, Graziella

AU - Montrucchio, Giuseppe

AU - Greco, Elisabetta

AU - Tizzani, Pietro

AU - Fera, Giacomo

AU - Di Luca, Maria Loreta

AU - Renna, Donatella

AU - Perciccante, Antonio

AU - Coralli, Alessia

AU - Tassara, Rodolfo

AU - Melis, Deborah

AU - Rebella, Lara

AU - Menardo, Giorgio

AU - Bottone, Stefania

AU - Sferrazzo, Elsa

AU - Ferri, Claudio

AU - Striuli, Rinaldo

AU - Scipioni, Rosa

AU - Salmi, Raffaella

AU - Gaudenzi, Piergiorgio

AU - Gamberini, Susanna

AU - Ricci, Franco

AU - Morabito, Cosimo

AU - Fava, Roberto

AU - Semplicini, Andrea

AU - Gottardo, Lucia

AU - Vendemiale, Gianluigi

AU - Serviddio, Gaetano

AU - Forlano, Roberta

AU - Bolondi, Luigi

AU - Rasciti, Leonardo

AU - Serio, Ilaria

AU - Masala, Cesare

AU - Mammarella, Antonio

AU - Raparelli, Valeria

AU - Fanelli, Filippo Rossi

AU - Delfino, Massimo

AU - Amoroso, Antonio

AU - Violi, Francesco

AU - Basili, Stefania

AU - Perri, Ludovica

AU - Serra, Pietro

AU - Fontana, Vincenzo

AU - Falcone, Marco

AU - Landolfi, Raffaele

AU - Grieco, Antonio

AU - Gallo, Antonella

AU - Zuccalà, Giuseppe

AU - Franceschi, Francesco

AU - De Marco, Guido

AU - Chiara, Cordischi

AU - Marta, Sabbatini

AU - Bellusci, Martino

AU - Setti, Donatella

AU - Pedrazzoli, Filippo

AU - Romanelli, Giuseppe

AU - Pirali, Caterina

AU - Amolini, Claudia

AU - Rosei, Enrico Agabiti

AU - Rizzoni, Damiano

AU - Castoldi, Luana

AU - Picardi, Antonio

AU - Gentilucci, Umberto Vespasiani

AU - Mazzarelli, Chiara

AU - Gallo, Paolo

AU - Guasti, Luigina

AU - Castiglioni, Luana

AU - Maresca, Andrea

AU - Squizzato, Alessandro

AU - Contini, Sara

AU - Molaro, Marta

AU - Annoni, Giorgio

AU - Corsi, Maurizio

AU - Zazzetta, Sara

AU - Bertolotti, Marco

AU - Mussi, Chiara

AU - Scotto, Roberto

AU - Ferri, Maria Alice

AU - Veltri, Francesca

AU - Arturi, Franco

AU - Succurro, Elena

AU - Sesti, Giorgio

AU - Gualtieri, Umberto

AU - Perticone, Francesco

AU - Sciacqua, Angela

AU - Quero, Michele

AU - Bagnato, Chiara

AU - Loria, Paola

AU - Becchi, Maria Angela

AU - Martucci, Gianfranco

AU - Fantuzzi, Alessandra

AU - Maurantonio, Mauro

AU - Corinaldesi, Roberto

AU - De Giorgio, Roberto

AU - Serra, Mauro

AU - Grasso, Valentina

AU - Ruggeri, Eugenio

AU - Carozza, Lorenzo Mauro

AU - Pignatti, Fabio

PY - 2015/6/1

Y1 - 2015/6/1

N2 - Background: Few studies evaluated the clinical outcomes of Community Acquired Pneumonia (CAP), Hospital-Acquired Pneumonia (HAP) and Health Care-Associated Pneumonia (HCAP) in relation to the adherence of antibiotic treatment to the guidelines of the Infectious Diseases Society of America (IDSA) and the American Thoracic Society (ATS) in hospitalized elderly people (65 years or older). Methods: Data were obtained from REPOSI, a prospective registry held in 87 Italian internal medicine and geriatric wards. Patients with a diagnosis of pneumonia (ICD-9 480-487) or prescribed with an antibiotic for pneumonia as indication were selected. The empirical antibiotic regimen was defined to be adherent to guidelines if concordant with the treatment regimens recommended by IDSA/ATS for CAP, HAP, and HCAP. Outcomes were assessed by logistic regression models. Results: A diagnosis of pneumonia was made in 317 patients. Only 38.8% of them received an empirical antibiotic regimen that was adherent to guidelines. However, no significant association was found between adherence to guidelines and outcomes. Having HAP, older age, and higher CIRS severity index were the main factors associated with in-hospital mortality. Conclusions: The adherence to antibiotic treatment guidelines was poor, particularly for HAP and HCAP, suggesting the need for more adherence to the optimal management of antibiotics in the elderly with pneumonia.

AB - Background: Few studies evaluated the clinical outcomes of Community Acquired Pneumonia (CAP), Hospital-Acquired Pneumonia (HAP) and Health Care-Associated Pneumonia (HCAP) in relation to the adherence of antibiotic treatment to the guidelines of the Infectious Diseases Society of America (IDSA) and the American Thoracic Society (ATS) in hospitalized elderly people (65 years or older). Methods: Data were obtained from REPOSI, a prospective registry held in 87 Italian internal medicine and geriatric wards. Patients with a diagnosis of pneumonia (ICD-9 480-487) or prescribed with an antibiotic for pneumonia as indication were selected. The empirical antibiotic regimen was defined to be adherent to guidelines if concordant with the treatment regimens recommended by IDSA/ATS for CAP, HAP, and HCAP. Outcomes were assessed by logistic regression models. Results: A diagnosis of pneumonia was made in 317 patients. Only 38.8% of them received an empirical antibiotic regimen that was adherent to guidelines. However, no significant association was found between adherence to guidelines and outcomes. Having HAP, older age, and higher CIRS severity index were the main factors associated with in-hospital mortality. Conclusions: The adherence to antibiotic treatment guidelines was poor, particularly for HAP and HCAP, suggesting the need for more adherence to the optimal management of antibiotics in the elderly with pneumonia.

KW - Antibiotics

KW - Elderly

KW - Guidelines adherence

KW - Mortality

KW - Pneumonia

KW - Re-hospitalization

UR - http://www.scopus.com/inward/record.url?scp=84981276310&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84981276310&partnerID=8YFLogxK

U2 - 10.1016/j.ejim.2015.04.002

DO - 10.1016/j.ejim.2015.04.002

M3 - Article

C2 - 25898778

AN - SCOPUS:84981276310

VL - 26

SP - 330

EP - 337

JO - European Journal of Internal Medicine

JF - European Journal of Internal Medicine

SN - 0953-6205

IS - 5

ER -