Adherence to highly active antiretroviral therapy is better in patients receiving non-nucleoside reverse transcriptase inhibitor-containing regimens than in those receiving protease inhibitor-containing regimens

Maria Paola Trotta, Adriana Ammassari, Alessandro Cozzi-Lepri, Mauro Zaccarelli, Francesco Castelli, Pasquale Narciso, Sara Melzi, Andrea De Luca, Antonella D'Arminio Monforte, Andrea Antinori

Research output: Contribution to journalArticle

Abstract

The difference between adherence to non-nucleoside reverse transcriptase inhibitor (NNRTI) and protease inhibitor (PI)-based regimens was investigated. Better adherence was found in NNRTI-treated patients, especially when efavirenz was included in the regimen, compared with single PI-treated patients and in those with CD4 cell counts less than 200 × 106/1. By contrast, younger age, self-report of active drug use, fatigue or vomiting negatively affected adherence. Self-reported sexual dysfunction was significantly associated with non-adherence only in PI-treated individuals.

Original languageEnglish
Pages (from-to)1099-1102
Number of pages4
JournalAIDS (London, England)
Volume17
Issue number7
DOIs
Publication statusPublished - May 2 2003

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

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