Adhesion to a polymeric biomaterial affects the antibiotic resistance of Staphylococcus epidermidis

C. R. Arciola, M. E. Donati, L. Montanaro

Research output: Contribution to journalArticle

Abstract

The antibiotic-resistance both of adherent bacteria to polymethylmethacrylate (PMMA) and of bacteria which, although exposed to the material, had not undergone adhesion, was measured as bacterial growth inhibition area onto a plate antibiogram, according to Kirby-Bauer and using a dedicated image analyzer system. The adhesion onto PMMA induces a marked (about 30%) increase in resistance to β-lactam antibiotics (cefamandole, cefazolin, imipenem and ampicillin) and a lower (about 15%) but significant increase to the macrolide erythromycin, to two aminoglycosides (amikacin, netilmicin) and to vancomycin, chloramphenicol and trimethoprim-sulfamethoxazole.

Original languageEnglish
Pages (from-to)63-68
Number of pages6
JournalNew Microbiologica
Volume24
Issue number1
Publication statusPublished - Jan 2001

Keywords

  • Antibiotic resistance
  • Bacterial adhesion
  • Biomaterials
  • Polymethylmethacrylate (PMMA)
  • Staphylococcus epidermidis

ASJC Scopus subject areas

  • Microbiology
  • Microbiology (medical)

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