Adiponectin, IL-10 and metabolic syndrome in obese children and adolescents

Valeria Calcaterra, Mara de Amici, Catherine Klersy, Cristina Torre, Vincenza Brizzi, Francesca Scaglia, Michela Albanesi, Riccardo Albertini, Benedetta Allais, Daniela Larizza

Research output: Contribution to journalArticle

Abstract

The metabolic syndrome (MetS) is a common basis for the development of atherogenic cardiovascular disease. Adiponectin has been demonstrated to be insulin-sensitizing and an anti-atherogenic factor and is considered a key of MetS. It was suggested that IL-10 may be involved in the inflammatory network of MetS in relation to adiponectin. We examined the relationship between adiponectin, IL-10 and MetS in pediatric obese patients. MetS components were assessed in 70 severely obese and 30 non-obese children and adolescents. Serum levels of adiponectin and IL-10 were measured in these subjects. Serum adiponectin levels were significantly lower (p

Original languageEnglish
Pages (from-to)117-123
Number of pages7
JournalActa Biomedica
Volume80
Issue number2
Publication statusPublished - 2009

Keywords

  • Adiponectin
  • Il-10
  • Metabolic syndrome
  • Obesity

ASJC Scopus subject areas

  • Medicine(all)

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