Abstract
We reevaluated the magnetic resonance (MR) examinations of 38 healthy volunteers (control group, CG) and of 124 patients with RV arrhythmia with left bundle branch block (LBBB) morphology: 45 with episodes of RV sustained tachycardia and of polymorphic RV premature beats (RVST-PPB group); 36 with only RV outflow tract sustained or not sustained tachycardia (RVOTT group); 43 with RV monomorphic premature beats (RVMPB group). All the examinations were reevaluated in a blinded fashion for detecting myocardial adipose replacement (AR) and wall bulges or aneurysms. In RVST-PPB patients, no AR was observed in 9%; 1 RV region involvement, 0%; 2 regions, 4%; ≥3 regions, 87%; left ventricle (LV), 15%. RVOTT patients: 0%, 53%, 14%, 5%, and 28%, respectively. RVMPB patients: 0%, 46%, 19%, 2%, and 33%, respectively. In CG, AR was observed in 11% (in RV outflow tract). RV bulges were detected in 80% of RVST-PPB, 39% of RVOTT, and 14% of RVMPB patients, none of the CG; RV aneurysms in 33% of RVST-PPB patients, none of RVOTT patients, RVMPB patients, and CG. A significant difference among groups for RV and LV AR as well as RV bulges and aneurysms was found (p <0.0001). In the direct comparisons, significant differences were found for: disease duration (RVST-PPB vs. RVMPB, p = 0.0396); RV AR (all the patients groups vs. CG, RVST-PPB vs. RVOTT or RVMPB, p <0.0001); RV aneurysms (RVST-PPB vs. CG, RVST-PPB vs. RVOTT or RVMPB, p <0.0002); bulges (all comparisons, p <0.0174). AR is confirmed as a structural substrate in RV arrhythmias. Number and extension of MR abnormalities are correlated to different degrees of RV arrhythmias.
| Original language | English |
|---|---|
| Pages (from-to) | 105-115 |
| Number of pages | 11 |
| Journal | The International Journal of Cardiac Imaging |
| Volume | 16 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - 2000 |
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Keywords
- Arrhythmogenic right ventricular cardiomyopathy
- Heart
- Magnetic resonance
- Right ventricle arrhythmyas
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging
- Cardiology and Cardiovascular Medicine
- Radiological and Ultrasound Technology
Cite this
Adipose replacement and wall motion abnormalities in right ventricle arrhythmias : Evaluation by MR imaging. Retrospective evaluation on 124 patients. / Molinari, Giuseppe; Sardanelli, Francesco; Zandrino, Franco; Parodi, Roberto C.; Bertero, Giovanni; Richiardi, Elena; Di Donna, Paolo; Gaita, Fiorenzo; Masperone, Maria A.
In: The International Journal of Cardiac Imaging, Vol. 16, No. 2, 2000, p. 105-115.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Adipose replacement and wall motion abnormalities in right ventricle arrhythmias
T2 - Evaluation by MR imaging. Retrospective evaluation on 124 patients
AU - Molinari, Giuseppe
AU - Sardanelli, Francesco
AU - Zandrino, Franco
AU - Parodi, Roberto C.
AU - Bertero, Giovanni
AU - Richiardi, Elena
AU - Di Donna, Paolo
AU - Gaita, Fiorenzo
AU - Masperone, Maria A.
PY - 2000
Y1 - 2000
N2 - We reevaluated the magnetic resonance (MR) examinations of 38 healthy volunteers (control group, CG) and of 124 patients with RV arrhythmia with left bundle branch block (LBBB) morphology: 45 with episodes of RV sustained tachycardia and of polymorphic RV premature beats (RVST-PPB group); 36 with only RV outflow tract sustained or not sustained tachycardia (RVOTT group); 43 with RV monomorphic premature beats (RVMPB group). All the examinations were reevaluated in a blinded fashion for detecting myocardial adipose replacement (AR) and wall bulges or aneurysms. In RVST-PPB patients, no AR was observed in 9%; 1 RV region involvement, 0%; 2 regions, 4%; ≥3 regions, 87%; left ventricle (LV), 15%. RVOTT patients: 0%, 53%, 14%, 5%, and 28%, respectively. RVMPB patients: 0%, 46%, 19%, 2%, and 33%, respectively. In CG, AR was observed in 11% (in RV outflow tract). RV bulges were detected in 80% of RVST-PPB, 39% of RVOTT, and 14% of RVMPB patients, none of the CG; RV aneurysms in 33% of RVST-PPB patients, none of RVOTT patients, RVMPB patients, and CG. A significant difference among groups for RV and LV AR as well as RV bulges and aneurysms was found (p <0.0001). In the direct comparisons, significant differences were found for: disease duration (RVST-PPB vs. RVMPB, p = 0.0396); RV AR (all the patients groups vs. CG, RVST-PPB vs. RVOTT or RVMPB, p <0.0001); RV aneurysms (RVST-PPB vs. CG, RVST-PPB vs. RVOTT or RVMPB, p <0.0002); bulges (all comparisons, p <0.0174). AR is confirmed as a structural substrate in RV arrhythmias. Number and extension of MR abnormalities are correlated to different degrees of RV arrhythmias.
AB - We reevaluated the magnetic resonance (MR) examinations of 38 healthy volunteers (control group, CG) and of 124 patients with RV arrhythmia with left bundle branch block (LBBB) morphology: 45 with episodes of RV sustained tachycardia and of polymorphic RV premature beats (RVST-PPB group); 36 with only RV outflow tract sustained or not sustained tachycardia (RVOTT group); 43 with RV monomorphic premature beats (RVMPB group). All the examinations were reevaluated in a blinded fashion for detecting myocardial adipose replacement (AR) and wall bulges or aneurysms. In RVST-PPB patients, no AR was observed in 9%; 1 RV region involvement, 0%; 2 regions, 4%; ≥3 regions, 87%; left ventricle (LV), 15%. RVOTT patients: 0%, 53%, 14%, 5%, and 28%, respectively. RVMPB patients: 0%, 46%, 19%, 2%, and 33%, respectively. In CG, AR was observed in 11% (in RV outflow tract). RV bulges were detected in 80% of RVST-PPB, 39% of RVOTT, and 14% of RVMPB patients, none of the CG; RV aneurysms in 33% of RVST-PPB patients, none of RVOTT patients, RVMPB patients, and CG. A significant difference among groups for RV and LV AR as well as RV bulges and aneurysms was found (p <0.0001). In the direct comparisons, significant differences were found for: disease duration (RVST-PPB vs. RVMPB, p = 0.0396); RV AR (all the patients groups vs. CG, RVST-PPB vs. RVOTT or RVMPB, p <0.0001); RV aneurysms (RVST-PPB vs. CG, RVST-PPB vs. RVOTT or RVMPB, p <0.0002); bulges (all comparisons, p <0.0174). AR is confirmed as a structural substrate in RV arrhythmias. Number and extension of MR abnormalities are correlated to different degrees of RV arrhythmias.
KW - Arrhythmogenic right ventricular cardiomyopathy
KW - Heart
KW - Magnetic resonance
KW - Right ventricle arrhythmyas
UR - http://www.scopus.com/inward/record.url?scp=0033948086&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0033948086&partnerID=8YFLogxK
U2 - 10.1023/A:1006304626233
DO - 10.1023/A:1006304626233
M3 - Article
VL - 16
SP - 105
EP - 115
JO - International Journal of Cardiovascular Imaging
JF - International Journal of Cardiovascular Imaging
SN - 1569-5794
IS - 2
ER -