Adipose tissue: From energy reservoir to a source of cells for epithelial tissue engineering

Angelo Trivisonno, Marc Abecassis, Massimo Monti, Gabriele Toietta, Athmani Bachir

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Adipose tissue is accessible with minimally invasive procedures, is abundant, and is replenishable. It consists of a heterogeneous cell population including preadipocytes, mature adipocytes, fibroblasts, vascular smooth muscle cells, endothelial cells, resident macrophages, and cells composing the stromal vascular fraction. This fraction contains multipotent cells with the same mesenchymal origin and similar biological and immunological characteristics of bone marrow stroma. On the other hand, adipose-derived stromal cells are easier to harvest and culture in comparison to bone marrow-derived ones. The authors discuss the microenvironment where are the stem cells is the niche, adipose tissue, and adipose tissue-derived stromal cell transplant for the treatment of epithelial pathologies, wound healing, diabetic foot, and other disorders.

Original languageEnglish
Title of host publicationStem Cells in Aesthetic Procedures: Art, Science, and Clinical Techniques
PublisherSpringer-Verlag Berlin Heidelberg
Pages303-326
Number of pages24
Volume9783642452079
ISBN (Print)9783642452079, 364245206X, 9783642452062
DOIs
Publication statusPublished - Nov 1 2014

ASJC Scopus subject areas

  • Medicine(all)

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