Adjuvant electrochemotherapy increases local control in a recurring equine anal melanoma

Licia Scacco, Carlo Bolaffio, Antonio Romano, Maurizio Fanciulli, Alfonso Baldi, Enrico Pierluigi Spugnini

Research output: Contribution to journalArticlepeer-review

Abstract

A 25-year-old gelding sport horse was referred for the treatment of recurring bilateral anal amelanotic melanoma. On physical examination, the horse presented bilateral poorly delimited perianal masses that recurred 2 months after surgical excision. The owner elected the lesions to be treated with surgery combined with electrochemotherapy using the drug cisplatin. The two masses were removed, and the surgical bed was treated with electrochemotherapy. A second session was performed 3 weeks later. The horse remained disease-free for 5 months and then experienced a marginal recurrence in one side. The nodule was re-treated, and the horse remained disease-free for 2 additional months, when it died of abdominal metastases. Electrochemotherapy can be added to the current strategies to palliate recurrent melanomas in horses.

Original languageEnglish
Pages (from-to)637-639
Number of pages3
JournalJournal of Equine Veterinary Science
Volume33
Issue number8
DOIs
Publication statusPublished - Aug 2013

Keywords

  • Anal melanoma
  • Biphasic pulses
  • Cisplatin
  • Electroporation
  • Horse

ASJC Scopus subject areas

  • Equine

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