ADJUVANTE SYSTEMISCHE THERAPIE BEIM MAMMAKARZINOM IN DEN NEUNZIGER JAHREN: STAND DER DINGE UND OFFENE FRAGEN

Translated title of the contribution: Adjuvant systemic therapy of breast cancer in the 1990s: Present situation and open questions

A. Goldhirsch, H. Neuenschwander, M. Castiglione, H. J. Senn, F. Cavalli

Research output: Contribution to journalArticle

Abstract

Adjuvant systemic therapy of breast cancer has been shown to reduce relapses and prolong survival in the women treated. This is true of all subpopulations studied. Six-month multidrug chemotherapy in premenopausal patients, and tamoxifen or shortterm chemotherapy in postmenopausal patients, are the treatments of choice in reducing the risk of relapse. In the near future ongoing research may answer some of the open questions surrounding the definition of populations for which the risk of relapse justifies therapy and the optimum manner of using available therapies. The modest but real improvement in prognosis of operable breast cancer was obtained solely by means of clinical trials. Participation in clinical research programs is becoming medically and socially mandatory.

Original languageGerman
Pages (from-to)1771-1783
Number of pages13
JournalSchweizerische Medizinische Wochenschrift
Volume120
Issue number47
Publication statusPublished - 1990

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ASJC Scopus subject areas

  • Medicine(all)

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