Adjuvant temozolomide chemotherapy for treatment of papillary tumor of the pineal region

Martin Lorenzetti; Federica Motta; Rolando Campanella; Dario Bauer; Agnese Assi; Cesare Arienta; Sergio Maria Gaini; Manuela Caroli

doi:10.1016/j.wneu.2010.10.039

Adjuvant temozolomide chemotherapy for treatment of papillary tumor of the pineal region

Martin Lorenzetti, Federica Motta, Rolando Campanella, Dario Bauer, Agnese Assi, Cesare Arienta, Sergio Maria Gaini, Manuela Caroli

Fondazione IRCCS Ca' Granda- Ospedale Maggiore Policlinico

Research output: Contribution to journal › Article › peer-review

Abstract

Background We present a personal case of papillary pineocytoma in a 42-year-old woman. Methods The lesion was first treated surgically both for diagnostic aims and for resolution of the mass effect causing hydrocephalus and correlated neurological disturbances. Because the tumor recurred after surgery and radiotherapy, we decided to further treat the patient with chemotherapy, in particular with temozolomide. Results Currently, almost 9 years after the first treatment, the patient is symptom-free and follow-up magnetic resonance imaging shows no tumor recurrence. Conclusion Although surgery should be considered the first-choice therapy, we think that temozolomide can be a valid option in case of recurrence of these rare tumors.

Original language	English
Pages (from-to)	160-163
Number of pages	4
Journal	World Neurosurgery
Volume	76
Issue number	1-2
DOIs	https://doi.org/10.1016/j.wneu.2010.10.039
Publication status	Published - Jul 2011

Keywords

Chemotherapy
Papillary pineocytoma
Papillary tumor of the pineal region
Temozolomide

ASJC Scopus subject areas

Clinical Neurology
Surgery

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title = "Adjuvant temozolomide chemotherapy for treatment of papillary tumor of the pineal region",

abstract = "Background We present a personal case of papillary pineocytoma in a 42-year-old woman. Methods The lesion was first treated surgically both for diagnostic aims and for resolution of the mass effect causing hydrocephalus and correlated neurological disturbances. Because the tumor recurred after surgery and radiotherapy, we decided to further treat the patient with chemotherapy, in particular with temozolomide. Results Currently, almost 9 years after the first treatment, the patient is symptom-free and follow-up magnetic resonance imaging shows no tumor recurrence. Conclusion Although surgery should be considered the first-choice therapy, we think that temozolomide can be a valid option in case of recurrence of these rare tumors.",

keywords = "Chemotherapy, Papillary pineocytoma, Papillary tumor of the pineal region, Temozolomide",

author = "Martin Lorenzetti and Federica Motta and Rolando Campanella and Dario Bauer and Agnese Assi and Cesare Arienta and Gaini, {Sergio Maria} and Manuela Caroli",

year = "2011",

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doi = "10.1016/j.wneu.2010.10.039",

language = "English",

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T1 - Adjuvant temozolomide chemotherapy for treatment of papillary tumor of the pineal region

AU - Lorenzetti, Martin

AU - Motta, Federica

AU - Campanella, Rolando

AU - Bauer, Dario

AU - Assi, Agnese

AU - Arienta, Cesare

AU - Gaini, Sergio Maria

AU - Caroli, Manuela

PY - 2011/7

Y1 - 2011/7

N2 - Background We present a personal case of papillary pineocytoma in a 42-year-old woman. Methods The lesion was first treated surgically both for diagnostic aims and for resolution of the mass effect causing hydrocephalus and correlated neurological disturbances. Because the tumor recurred after surgery and radiotherapy, we decided to further treat the patient with chemotherapy, in particular with temozolomide. Results Currently, almost 9 years after the first treatment, the patient is symptom-free and follow-up magnetic resonance imaging shows no tumor recurrence. Conclusion Although surgery should be considered the first-choice therapy, we think that temozolomide can be a valid option in case of recurrence of these rare tumors.

AB - Background We present a personal case of papillary pineocytoma in a 42-year-old woman. Methods The lesion was first treated surgically both for diagnostic aims and for resolution of the mass effect causing hydrocephalus and correlated neurological disturbances. Because the tumor recurred after surgery and radiotherapy, we decided to further treat the patient with chemotherapy, in particular with temozolomide. Results Currently, almost 9 years after the first treatment, the patient is symptom-free and follow-up magnetic resonance imaging shows no tumor recurrence. Conclusion Although surgery should be considered the first-choice therapy, we think that temozolomide can be a valid option in case of recurrence of these rare tumors.

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KW - Papillary tumor of the pineal region

KW - Temozolomide

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