Adjuvant temozolomide chemotherapy for treatment of papillary tumor of the pineal region

Martin Lorenzetti, Federica Motta, Rolando Campanella, Dario Bauer, Agnese Assi, Cesare Arienta, Sergio Maria Gaini, Manuela Caroli

Research output: Contribution to journalArticlepeer-review


Background We present a personal case of papillary pineocytoma in a 42-year-old woman. Methods The lesion was first treated surgically both for diagnostic aims and for resolution of the mass effect causing hydrocephalus and correlated neurological disturbances. Because the tumor recurred after surgery and radiotherapy, we decided to further treat the patient with chemotherapy, in particular with temozolomide. Results Currently, almost 9 years after the first treatment, the patient is symptom-free and follow-up magnetic resonance imaging shows no tumor recurrence. Conclusion Although surgery should be considered the first-choice therapy, we think that temozolomide can be a valid option in case of recurrence of these rare tumors.

Original languageEnglish
Pages (from-to)160-163
Number of pages4
JournalWorld Neurosurgery
Issue number1-2
Publication statusPublished - Jul 2011


  • Chemotherapy
  • Papillary pineocytoma
  • Papillary tumor of the pineal region
  • Temozolomide

ASJC Scopus subject areas

  • Clinical Neurology
  • Surgery


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