Abstract
The object of Ludwig III was to assess adjuvant therapy after total mastectomy and axillary clearance in postmenopausal women with breast cancer and axillary node metastases. Chemo-endocrine therapy (cyclophosphamide, methotrexate, 5-fluorouracil, prednisone and tamoxifen: CMFp + T) was compared with endocrine therapy (prednisone and tamoxifen: p + T) and with no adjuvant treatment in 463 evaluable patients aged 65 years or less. Treatment results are available (Ludwig Breast Cancer Study Group, Lancet i (1984) 1256-1260). Nodal status and receptor content of the primary were found to have prognostic value, while tumor size did not.
| Original language | English |
|---|---|
| Pages (from-to) | 1155-1160 |
| Number of pages | 6 |
| Journal | Journal of Steroid Biochemistry |
| Volume | 23 |
| Issue number | 6 PART 2 |
| DOIs | |
| Publication status | Published - 1985 |
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ASJC Scopus subject areas
- Biochemistry
- Endocrinology
Cite this
Adjuvant treatment in operable breast cancer. / Goldhirsch, A.
In: Journal of Steroid Biochemistry, Vol. 23, No. 6 PART 2, 1985, p. 1155-1160.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Adjuvant treatment in operable breast cancer
AU - Goldhirsch, A.
PY - 1985
Y1 - 1985
N2 - The object of Ludwig III was to assess adjuvant therapy after total mastectomy and axillary clearance in postmenopausal women with breast cancer and axillary node metastases. Chemo-endocrine therapy (cyclophosphamide, methotrexate, 5-fluorouracil, prednisone and tamoxifen: CMFp + T) was compared with endocrine therapy (prednisone and tamoxifen: p + T) and with no adjuvant treatment in 463 evaluable patients aged 65 years or less. Treatment results are available (Ludwig Breast Cancer Study Group, Lancet i (1984) 1256-1260). Nodal status and receptor content of the primary were found to have prognostic value, while tumor size did not.
AB - The object of Ludwig III was to assess adjuvant therapy after total mastectomy and axillary clearance in postmenopausal women with breast cancer and axillary node metastases. Chemo-endocrine therapy (cyclophosphamide, methotrexate, 5-fluorouracil, prednisone and tamoxifen: CMFp + T) was compared with endocrine therapy (prednisone and tamoxifen: p + T) and with no adjuvant treatment in 463 evaluable patients aged 65 years or less. Treatment results are available (Ludwig Breast Cancer Study Group, Lancet i (1984) 1256-1260). Nodal status and receptor content of the primary were found to have prognostic value, while tumor size did not.
UR - http://www.scopus.com/inward/record.url?scp=0022310058&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0022310058&partnerID=8YFLogxK
U2 - 10.1016/0022-4731(85)90036-6
DO - 10.1016/0022-4731(85)90036-6
M3 - Article
C2 - 3912622
AN - SCOPUS:0022310058
VL - 23
SP - 1155
EP - 1160
JO - Journal of Steroid Biochemistry
JF - Journal of Steroid Biochemistry
SN - 0022-4731
IS - 6 PART 2
ER -