Abstract
The object of Ludwig III was to assess adjuvant therapy after total mastectomy and axillary clearance in postmenopausal women with breast cancer and axillary node metastases. Chemo-endocrine therapy (cyclophosphamide, methotrexate, 5-fluorouracil, prednisone and tamoxifen: CMFp + T) was compared with endocrine therapy (prednisone and tamoxifen: p + T) and with no adjuvant treatment in 463 evaluable patients aged 65 years or less. Treatment results are available (Ludwig Breast Cancer Study Group, Lancet i (1984) 1256-1260). Nodal status and receptor content of the primary were found to have prognostic value, while tumor size did not.
| Original language | English |
|---|---|
| Pages (from-to) | 1155-1160 |
| Number of pages | 6 |
| Journal | Journal of Steroid Biochemistry |
| Volume | 23 |
| Issue number | 6 PART 2 |
| DOIs | |
| Publication status | Published - 1985 |
ASJC Scopus subject areas
- Biochemistry
- Endocrinology
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Cite this
Goldhirsch, A. (1985). Adjuvant treatment in operable breast cancer. Journal of Steroid Biochemistry, 23(6 PART 2), 1155-1160. https://doi.org/10.1016/0022-4731(85)90036-6