Adrenomedullin blood concentrations in infants subjected to cardiopulmonary bypass: Correlation with monitoring parameters and prediction of poor neurological outcome

Pasquale Florio, Raul Abella, Emanuela Marinoni, Romolo Di Iorio, Claudio Letizia, Marco Meli, Teresa De La Torre, Felice Petraglia, Alessandro Cazzaniga, Alessandro Giamberti, Alessandro Frigiola, Diego Gazzolo

Research output: Contribution to journalArticlepeer-review

Abstract

BACKGROUND: Brain injury is a major adverse event after cardiac surgery, especially when extracorporeal circuits are used. We evaluated whether cardiopulmonary bypass (CPB) affects cerebrovascular resistance and plasma concentrations of adrenomedullin (AM), a vasoactive peptide regulating cerebral blood flow. METHODS: We evaluated 50 infants (age

Original languageEnglish
Pages (from-to)202-206
Number of pages5
JournalClinical Chemistry
Volume54
Issue number1
DOIs
Publication statusPublished - Jan 1 2008

ASJC Scopus subject areas

  • Clinical Biochemistry

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