Adult granulosa cell tumor of the ovary: A clinico pathologic study of 35 cases

Rosanna Fontanelli, Bernardina Stefanon, Francesco Raspagliesi, Rado Kenda, Gorana Tomasic, Giovanbattista Spatti, Gianluca Riboldi, Patrizia Di Donato, Silvana Pilotti, Giuseppe De Palo

Research output: Contribution to journalArticlepeer-review

Abstract

Aims and background: Adult granulosa cell tumor has a low malignant potential but requires an extensive follow-up of more than 5 years to accurately assess tumor activity. The aim of the present study was to evaluate the clinical characteristics, the treatment and the outcome of this rare ovarian tumor. Study design: A retrospective review of 36 cases treated at primary onset of disease during a 23-year period from 1971 to 1993. Results: The disease-free survival rate for stages A-B-C at 5 and 10 years was 90% and 64%, respectively, for stages III-IV the 5-year freedom from progression rate was 16%. Conclusions: The most important prognostic factor appears to be the extent of tumor involvement outside of the ovary.

Original languageEnglish
Pages (from-to)60-64
Number of pages5
JournalTumori
Volume84
Issue number1
Publication statusPublished - Jan 1998

Keywords

  • Adult granulosa cell tumor
  • Ovary
  • Prognosis

ASJC Scopus subject areas

  • Cancer Research

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