Adult height in patients treated for isolated growth hormone deficiency: Role of birth weight

Alessandra Di Cesare Merlone, Elena Bozzola, Claudia Castelnovi, Patrizia Chiabotto, Laura Costante, Luisa De Sanctis, Carmine Tinelli, Mauro Bozzola

Research output: Contribution to journalArticle


To evaluate the effect of growth hormone (GH) administration on adult height (AH) in two groups of isolated GH-deficient (IGHD) children born either small (birth weight below -2 SD) or appropriate (birth weight above -2 SD) for gestational age (GA). Out of 35 prepubertal IGHD children, 14 small for GA (SGA, group A) and 21 appropriate for GA (AGA, group B) were examined. All patients received continuous GH treatment at a median dose of 0.028 mg/kg/day (range 0.023-0.032) in group A and 0.024 (range 0.023-0.028) in group B. GH treatment was administered for a period of 67.0 months (range 42.37-96.05) in group A and 54.31 months (range 47.14-69.31) in group B. All children were measured using a Harpenden stadiometer every 6 months until they reached AH (growth velocity

Original languageEnglish
Pages (from-to)102-106
Number of pages5
JournalHormone Research
Issue number2
Publication statusPublished - 2005



  • Adult height
  • Appropriate for gestational age
  • Growth hormone deficiency
  • Small for gestational age

ASJC Scopus subject areas

  • Endocrinology

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