Background: Adult-onset foveomacular vitelliform dystrophy (AOFVD) represents a heterogeneous group of disorders with different clinical, angiographic, and histopathological features. The most common form is characterized by a yellow, round to oval subretinal macular lesion with or without central pigmented spot. Methods: Eight patients affected by typical AOFVD underwent fluorescein angiography and indocyanine green videoangiography (ICGV). Results: Fluorescein angiography showed a central hypofluorescent spot surrounded by an irregular hyperfluorescent ring. ICGV demonstrated a foveal nonfluorescent spot, visible during the entire examination, and a hyperfluorescent area surrounding the central spot, which became evident soon after the beginning of the examination. Conclusions: In light of previous histopathological studies, the central nonfluorescent spot may be interpreted as a masking effect of a pigment clump, whereas the hyperfluorescent area may represent dye pooling or staining of the subretinal pigment epithelial material.
|Number of pages||4|
|Journal||Graefe's Archive for Clinical and Experimental Ophthalmology|
|Publication status||Published - Mar 1996|
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