Adult to Adult Living Donor Liver Transplantation in Recipients with Low MELD: A Strategy Intended to Overcome Donor Shortage

Salvatore Gruttadauria, Duilio Pagano, Fabrizio di Francesco, Aaron Foglio, Calogero Cammà, Vito Di Marco, Ioannis Petridis, Davide Cintorino

Research output: Contribution to journalArticlepeer-review

Abstract

Recent series have demonstrated advantages of living donor over deceased donor liver transplantation, with particular benefit for those with low model for end-stage liver disease score. The logic underlying the transplantation of patients before they become too sick is intuitive. It reduces mortality and drop outs from the waiting list and makes transplant surgery less demanding. Those principles have to be balanced with donor safety and transplant benefit for the recipient avoiding early, futile transplantation. The authors report a case of adult to adult right lobe living donor liver transplantation performed for a recipient affected by primary biliary cirrhosis with MELD score of 15, in a transplant center located in an area of Europe characterized by chronic organ shortage.

Original languageEnglish
Pages (from-to)3477-3480
Number of pages4
JournalDigestive Diseases and Sciences
Volume65
Issue number12
DOIs
Publication statusPublished - Dec 2020

Keywords

  • Adult
  • Clinical Decision-Making
  • Cone-Beam Computed Tomography/methods
  • End Stage Liver Disease/diagnosis
  • Female
  • Hepatectomy/methods
  • Humans
  • Italy
  • Liver/diagnostic imaging
  • Liver Cirrhosis, Biliary/complications
  • Liver Transplantation/adverse effects
  • Living Donors/supply & distribution
  • Male
  • Middle Aged
  • Pleural Effusion/etiology
  • Postoperative Complications/therapy
  • Risk Adjustment/methods
  • Severity of Illness Index
  • Time-to-Treatment/standards
  • Tissue and Organ Procurement/statistics & numerical data
  • Treatment Outcome

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