TY - JOUR
T1 - Advance in the treatment of aneurysmal bone cyst of the sacrum
AU - Donati, Davide
AU - Frisoni, Tommaso
AU - Dozza, Barbara
AU - Degroot, Henry
AU - Albisinni, Ugo
AU - Giannini, Sandro
PY - 2011/11
Y1 - 2011/11
N2 - Objective: The objective of this study was the review of 11 patients with two different treatment methods used historically for aneurysmal bone cyst in the sacrum. The outcome of both procedures is reported. In addition, the treatment technique of CT-guided percutaneous injections of demineralized bone matrix mixed with bone marrow concentrate is described. Materials and methods: From 1997 to 2008, 11 patients with sacral aneurysmal bone cyst were treated at the Rizzoli Institute, Bologna, Italy. The first seven patients had surgical curettage without bone grafting, chemical adjuvants, or arterial embolization. The last four patients had arterial embolization. The last patient did not respond to arterial embolization and was treated by CT-guided injection of demineralized bone matrix mixed with bone marrow concentrate. Results: Curettage was successful in five out of seven patients. Two patients suffered complications, and two cases had recurrence. Arterial embolization was successful in three of four patients. The patient treated with injection had a good clinical and radiographic result. Conclusion: Both surgical and arterial embolization are effective for aneurysmal bone cyst in the sacrum. However, these treatments may lead to complications and recurrence. The use of CT-guided injections of demineralized bone matrix mixed with bone marrow concentrate may be a safe and effective alternative for treatment of these destructive and problematic lesions.
AB - Objective: The objective of this study was the review of 11 patients with two different treatment methods used historically for aneurysmal bone cyst in the sacrum. The outcome of both procedures is reported. In addition, the treatment technique of CT-guided percutaneous injections of demineralized bone matrix mixed with bone marrow concentrate is described. Materials and methods: From 1997 to 2008, 11 patients with sacral aneurysmal bone cyst were treated at the Rizzoli Institute, Bologna, Italy. The first seven patients had surgical curettage without bone grafting, chemical adjuvants, or arterial embolization. The last four patients had arterial embolization. The last patient did not respond to arterial embolization and was treated by CT-guided injection of demineralized bone matrix mixed with bone marrow concentrate. Results: Curettage was successful in five out of seven patients. Two patients suffered complications, and two cases had recurrence. Arterial embolization was successful in three of four patients. The patient treated with injection had a good clinical and radiographic result. Conclusion: Both surgical and arterial embolization are effective for aneurysmal bone cyst in the sacrum. However, these treatments may lead to complications and recurrence. The use of CT-guided injections of demineralized bone matrix mixed with bone marrow concentrate may be a safe and effective alternative for treatment of these destructive and problematic lesions.
KW - Aneurysmal bone cyst
KW - Pseudo tumoral lesion
KW - Regenerative medicine
KW - Sacral location
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U2 - 10.1007/s00256-011-1202-7
DO - 10.1007/s00256-011-1202-7
M3 - Article
C2 - 21626181
AN - SCOPUS:80755140154
VL - 40
SP - 1461
EP - 1466
JO - Skeletal Radiology
JF - Skeletal Radiology
SN - 0364-2348
IS - 11
ER -