Abstract
Non-dystrophic (NDMs) and Dystrophic Myotonias (DMs) are diseases characterized by the presence of myotonia with or without muscle weakness. A standardized myotonia assessment is important to more objectively quantify the handgrip myotonia. We screened 10 patients affected by NDM and 10 patients with DM, using the sensor-engineered glove (SEG). The time required to perform a complete finger extension (grip myotonia time, GMT) at maximum velocity (MV) after maximum voluntary contraction (MVC) was evaluated through an ad hoc protocol including rest, exercise, and ice effects on handgrip myotonia. We observed a general trend to GMT increase when applying the ice block and a GMT decrease when repeating GM movements, at individual level in both NDM and DM patients. SEG is an automated, non-invasive, quick, and easy technique for evaluating handgrip myotonia in NDM and DM patients. SEG could, therefore, be considered a promising tool to evaluate myotonia and monitor treatment efficacy for clinical trials.
| Original language | English |
|---|---|
| Pages (from-to) | 3-7 |
| Number of pages | 5 |
| Journal | Journal of the Neurological Sciences |
| Volume | 375 |
| DOIs | |
| Publication status | Published - Apr 15 2017 |
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Keywords
- Adolescent
- Adult
- Biomedical Engineering
- Diagnostic Techniques, Neurological
- Equipment and Supplies
- Female
- Hand Strength
- Humans
- Male
- Middle Aged
- Muscle Contraction
- Muscle, Skeletal
- Myotonia
- Young Adult
- Journal Article
Cite this
Advances in assessing myotonia: Can sensor-engineered glove have a role? / Portaro, Simona; Russo, Margherita; Naro, Antonino; Bramanti, Alessia; Bramanti, Placido; Rodolico, Carmelo; Calabrò, Rocco Salvatore.
In: Journal of the Neurological Sciences, Vol. 375, 15.04.2017, p. 3-7.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Advances in assessing myotonia: Can sensor-engineered glove have a role?
AU - Portaro, Simona
AU - Russo, Margherita
AU - Naro, Antonino
AU - Bramanti, Alessia
AU - Bramanti, Placido
AU - Rodolico, Carmelo
AU - Calabrò, Rocco Salvatore
N1 - Copyright © 2017 Elsevier B.V. All rights reserved.
PY - 2017/4/15
Y1 - 2017/4/15
N2 - Non-dystrophic (NDMs) and Dystrophic Myotonias (DMs) are diseases characterized by the presence of myotonia with or without muscle weakness. A standardized myotonia assessment is important to more objectively quantify the handgrip myotonia. We screened 10 patients affected by NDM and 10 patients with DM, using the sensor-engineered glove (SEG). The time required to perform a complete finger extension (grip myotonia time, GMT) at maximum velocity (MV) after maximum voluntary contraction (MVC) was evaluated through an ad hoc protocol including rest, exercise, and ice effects on handgrip myotonia. We observed a general trend to GMT increase when applying the ice block and a GMT decrease when repeating GM movements, at individual level in both NDM and DM patients. SEG is an automated, non-invasive, quick, and easy technique for evaluating handgrip myotonia in NDM and DM patients. SEG could, therefore, be considered a promising tool to evaluate myotonia and monitor treatment efficacy for clinical trials.
AB - Non-dystrophic (NDMs) and Dystrophic Myotonias (DMs) are diseases characterized by the presence of myotonia with or without muscle weakness. A standardized myotonia assessment is important to more objectively quantify the handgrip myotonia. We screened 10 patients affected by NDM and 10 patients with DM, using the sensor-engineered glove (SEG). The time required to perform a complete finger extension (grip myotonia time, GMT) at maximum velocity (MV) after maximum voluntary contraction (MVC) was evaluated through an ad hoc protocol including rest, exercise, and ice effects on handgrip myotonia. We observed a general trend to GMT increase when applying the ice block and a GMT decrease when repeating GM movements, at individual level in both NDM and DM patients. SEG is an automated, non-invasive, quick, and easy technique for evaluating handgrip myotonia in NDM and DM patients. SEG could, therefore, be considered a promising tool to evaluate myotonia and monitor treatment efficacy for clinical trials.
KW - Adolescent
KW - Adult
KW - Biomedical Engineering
KW - Diagnostic Techniques, Neurological
KW - Equipment and Supplies
KW - Female
KW - Hand Strength
KW - Humans
KW - Male
KW - Middle Aged
KW - Muscle Contraction
KW - Muscle, Skeletal
KW - Myotonia
KW - Young Adult
KW - Journal Article
U2 - 10.1016/j.jns.2017.01.038
DO - 10.1016/j.jns.2017.01.038
M3 - Article
VL - 375
SP - 3
EP - 7
JO - Journal of the Neurological Sciences
JF - Journal of the Neurological Sciences
SN - 0022-510X
ER -