TY - JOUR
T1 - Advances in the changing patterns of aetiology of head and neck cancers
AU - Licitra, Lisa
AU - Rossini, Chiara
AU - Bossi, Paolo
AU - Locati, Laura D.
PY - 2006/4
Y1 - 2006/4
N2 - Purpose of review: Recent cumulated evidence suggests that factors other than those conventionally known may contribute to the development of head and neck cancer. In fact, a review of the most recent literature shows interesting advances in molecular epidemiology. Recent findings: Recent studies have pointed out the role both of exposure to carcinogens and of an inherited or acquired genetic susceptibility. A very broad mechanism by which gene families can be responsible for the disease has been depicted. This mechanism ranges from behaviour genes, which can regulate lifestyle habits, to metabolizing genes, DNA repair genes and cell cycle control genes. Summary: This review tries to summarize the most recent advances in the field of cancerogenesis in head and neck cancer.
AB - Purpose of review: Recent cumulated evidence suggests that factors other than those conventionally known may contribute to the development of head and neck cancer. In fact, a review of the most recent literature shows interesting advances in molecular epidemiology. Recent findings: Recent studies have pointed out the role both of exposure to carcinogens and of an inherited or acquired genetic susceptibility. A very broad mechanism by which gene families can be responsible for the disease has been depicted. This mechanism ranges from behaviour genes, which can regulate lifestyle habits, to metabolizing genes, DNA repair genes and cell cycle control genes. Summary: This review tries to summarize the most recent advances in the field of cancerogenesis in head and neck cancer.
KW - Carcinogens
KW - Head and neck cancer
KW - Molecular epidemiology
UR - http://www.scopus.com/inward/record.url?scp=33646021650&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=33646021650&partnerID=8YFLogxK
U2 - 10.1097/01.moo.0000193170.23956.5f
DO - 10.1097/01.moo.0000193170.23956.5f
M3 - Article
C2 - 16552266
AN - SCOPUS:33646021650
VL - 14
SP - 95
EP - 99
JO - Current Opinion in Otolaryngology and Head and Neck Surgery
JF - Current Opinion in Otolaryngology and Head and Neck Surgery
SN - 1068-9508
IS - 2
ER -