Reazioni indesiderate al vaccino pertosse a cellule intere: Problema medico o di sanita pubblica?

Translated title of the contribution: Adverse reactions to whole-cell pertussis vaccine: A medical or a public health problem?

A. E. Tozzi, M. L. Ciofi Degli Atti, S. Salmaso, P. Panei, A. Piscitelli, A. Anemona, P. Carbonari, S. G F Wassilak

Research output: Contribution to journalArticle

Abstract

An active surveillance of adverse events following whole-cell diphtheria-tetanus-pertussis immunization (DTP) in the first year of life and of the reasons for interruption of the immunization cycle has been conducted in the period September 1993-April 1995. One thousand seven hundred sixty- five children immunized with different DTP vaccine in the local health units of Veneto and Friuli Venezia Giulia regions participated in the study. Only 19.4% of children with interrupted immunization cycles had an appropriate reason for stopping pertussis vaccination. Moreover 54.2% of children with interrupted pertussis immunization stopped it because of a common adverse event which was not a true contraindication to the administration of further doses. Common adverse events following vaccination ranged from a minimum of 4% of the total doses had vomiting to 58% with irritability. The most frequent severe adverse event was persistent crying > 3 hours (in every 199 doses). Common adverse events following DTP, thugh not representing a true contraindication to the administration of further doses, are a common cause of interruption of the immunization cycle and an obstacle to parental acceptance of vaccination and high vaccination coverage.

Translated title of the contributionAdverse reactions to whole-cell pertussis vaccine: A medical or a public health problem?
Original languageItalian
Pages (from-to)401-408
Number of pages8
JournalIgiene Moderna
Volume111
Issue number4
Publication statusPublished - Apr 1999

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health

Fingerprint Dive into the research topics of 'Adverse reactions to whole-cell pertussis vaccine: A medical or a public health problem?'. Together they form a unique fingerprint.

  • Cite this

    Tozzi, A. E., Ciofi Degli Atti, M. L., Salmaso, S., Panei, P., Piscitelli, A., Anemona, A., Carbonari, P., & Wassilak, S. G. F. (1999). Reazioni indesiderate al vaccino pertosse a cellule intere: Problema medico o di sanita pubblica? Igiene Moderna, 111(4), 401-408.