The incidence of AED induced language disorders and the possible risk factors were investigated in 250 consecutive adult patients (pts), 132 M 118 F, 18-65 years of age. The following parameters were analysed: 1) EEG; 2) seizure type; 3) brain RM/TC; 4) SPECT; 5) therapy; 6) left-/right handed hemispheric dominance. 19 right-handed pts (7.6%) showed language disorders and SPECT/EEG/RM data revealed a left sided epileptogenic focus in 16 pts (84.2%) (p = 0.0004). The incidence of this unwanted effect was 7-8% and the presence of a left-sided epileptogenic focus was a risk factor. All AEDs were involved and the effect was unrelated to drug dosage.
|Translated title of the contribution||AED induced language disorders: A prospective analysis of risk factors|
|Number of pages||2|
|Journal||Bollettino - Lega Italiana contro l'Epilessia|
|Publication status||Published - Jul 2004|
ASJC Scopus subject areas
- Clinical Neurology