Affective and psychiatric disorders in celiac disease

Giovanni Addolorato, Lorenzo Leggio, Cristina D'Angelo, Antonio Mirijello, Anna Ferrulli, Silvia Cardone, Luisa Vonghia, Ludovico Abenavoli, Veruscka Leso, Antonio Nesci, Salvatore Piano, Esmeralda Capristo, Giovanni Gasbarrini

Research output: Contribution to journalArticlepeer-review


Several extraintestinal clinical manifestations have been reported in celiac disease (CD). Among them, growing evidence suggests the association between CD and affective and psychiatric disorders. In this review the most frequent affective and psychiatric disorders associated with CD and the possible mechanisms involved in these associations were analyzed. The available data suggest that screening for CD in patients with affective and/or psychiatric symptoms may be useful since these disorders could be the expression of an organic disease rather than primary psychiatric illnesses.

Original languageEnglish
Pages (from-to)140-148
Number of pages9
JournalDigestive Diseases
Issue number2
Publication statusPublished - Apr 2008


  • Affective disorders
  • Celiac disease
  • Gluten-free diet
  • Psychiatric disorders
  • Psychological support
  • Quality of life

ASJC Scopus subject areas

  • Gastroenterology


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