Afterdischarge activity in neuropathic patients with frequent muscle cramps

L. Parisi, M. Serrao, P. Rossi, G. Valente, F. Fattapposta, F. Pierelli, G. Amabile

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Objectives - To evaluate the presence of the afterdischarge activity following M- and F-waves in patients with peripheral neuropathies with or without muscle cramps. Material and methods - Ten patients with peripheral neuropathies complaining of frequent muscle leg cramps (Group 1) and 14 patients with peripheral neuropathies without muscle cramps (Group 2) participated in our study. The afterdischarge was evaluated through a repetitive stimulation of the peroneal and tibial nerves. Results - An abnormal afterdischarge activity following F-wave was identified below 5 Hz only in Group 1. On high frequency of stimulation (> 5 Hz), this activity was present in every patient in Group 1. Moreover, it was particularly present in the muscle affected by cramps. Conclusion - Since the afterdischarges following F-waves have been considered to be the result of a hyperactive 'bistable' state of alfa-motor neurons, our findings are indicative of an impairment of motor neuron excitability. Thus, it is hypothesizable that either peripheral and central mechanisms may together contribute in producing muscle cramps.

Original languageEnglish
Pages (from-to)359-362
Number of pages4
JournalActa Neurologica Scandinavica
Volume102
Issue number6
DOIs
Publication statusPublished - 2000

Fingerprint

Muscle Cramp
Peripheral Nervous System Diseases
Motor Neurons
Tibial Nerve
Peroneal Nerve
Leg

Keywords

  • Afterdischarge activity
  • Muscle cramps
  • Peripheral neuropathy

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)

Cite this

Afterdischarge activity in neuropathic patients with frequent muscle cramps. / Parisi, L.; Serrao, M.; Rossi, P.; Valente, G.; Fattapposta, F.; Pierelli, F.; Amabile, G.

In: Acta Neurologica Scandinavica, Vol. 102, No. 6, 2000, p. 359-362.

Research output: Contribution to journalArticle

Parisi, L, Serrao, M, Rossi, P, Valente, G, Fattapposta, F, Pierelli, F & Amabile, G 2000, 'Afterdischarge activity in neuropathic patients with frequent muscle cramps', Acta Neurologica Scandinavica, vol. 102, no. 6, pp. 359-362. https://doi.org/10.1034/j.1600-0404.2000.102006359.x
Parisi, L. ; Serrao, M. ; Rossi, P. ; Valente, G. ; Fattapposta, F. ; Pierelli, F. ; Amabile, G. / Afterdischarge activity in neuropathic patients with frequent muscle cramps. In: Acta Neurologica Scandinavica. 2000 ; Vol. 102, No. 6. pp. 359-362.
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