Age at onset and latency to treatment (duration of untreated illness) in patients with mood and anxiety disorders: A naturalistic study

Alfredo Carlo Altamura, Massimiliano Buoli, Alessandra Albano, Bernardo Dell'Osso

Research output: Contribution to journalArticlepeer-review

Abstract

This study was designed to investigate and compare demographic and clinical features with specific emphasis on age at onset, age at first treatment and, in particular, on duration of untreated illness (DUI), in patients with different mood and anxiety disorders. Study sample included 729 outpatients with the following diagnoses: major depressive disorder (n=181), bipolar disorder type I (BD I, n=115) and II (BD II, n=186), generalized anxiety disorder (n=100), panic disorder (n=96), and obsessive-compulsive disorder (n=51). Main demographic and clinical variables of the sample were compared among the diagnostic groups using one-way analysis of variance or χ tests. The diagnostic groups showed significant differences in relation to age at onset and age at first pharmacological treatment and in relation to latency to treatment. In particular, patients with major depressive disorder showed the shortest DUI (39.08 months), whereas patient with BD II showed the longest DUI (97.2 months) in comparison with the other groups. Within the group with anxiety disorders (F=7.512, P

Original languageEnglish
Pages (from-to)172-179
Number of pages8
JournalInternational Clinical Psychopharmacology
Volume25
Issue number3
DOIs
Publication statusPublished - May 2010

Keywords

  • Bipolar disorder
  • Duration of untreated illness
  • Generalized anxiety disorder
  • Major depressive disorder
  • Obsessive-compulsive disorder
  • Panic disorder

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Pharmacology (medical)

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