Age-dependent learning performance during development and aging in C57BL/6 mice

S. Fagioli, M. Ammassari-Teule, C. Rossi-Arnaud, C. Castellano

Research output: Contribution to journalArticlepeer-review


This experiment examined the retention of a passive avoidance response in 1-, 2-, 10- and 18-month-old C57BL/6 mice. Retention performance was assessed after training-test intervals of 24, 48 and 72 h. Adult (2 months) animals always reached the highest performance. At each interval the decline in retention performance (i.e. the rate of forgetting) varied according to the age group. With increasing testing intervals, the retention times of young, mature and old animals tended to become similar.

Original languageEnglish
Pages (from-to)247-250
Number of pages4
Issue number4
Publication statusPublished - 1992

ASJC Scopus subject areas

  • Geriatrics and Gerontology
  • Neuropsychology and Physiological Psychology


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