Abstract
Dose kinetics and side effects of viloxazine (VLX) in 16 healthy volunteers (range age 25-90 years) were studied after single oral administration of 200 mg of VLX. Significant differences in peak plasma values (P1/2 (P1/2 and Cl/F, due to the high interindividual variability in pharmacokinetic profiles. Total reported and observed side effects scores were higher overall in subjects under 50 years than over 60 years and were inversely correlated to AUC (P
Original language | English |
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Pages (from-to) | 281-285 |
Number of pages | 5 |
Journal | Psychopharmacology |
Volume | 81 |
Issue number | 4 |
DOIs | |
Publication status | Published - Nov 1983 |
Keywords
- Age
- Metabolites
- Pharmacokinetics
- Side effects
- Viloxazine
ASJC Scopus subject areas
- Pharmacology