Abstract
In vitro incubation induces, in rabbit red cell membranes, significant modifications consisting mainly in a decrease of sialic acid and galactose. In vivo the life span of incubated erythrocytes seems to be correlated to the degree of surface alterations and ATP depletion: larger surface modifications and energy charge reduction induce shorter survival time. It can therefore be postulated that incubation of red cell in vitro can cause an ageing process similar to that occurring physiologically in vivo.
| Original language | English |
|---|---|
| Pages (from-to) | 263-269 |
| Number of pages | 7 |
| Journal | Acta Haematologica |
| Volume | 65 |
| Issue number | 4 |
| Publication status | Published - 1981 |
ASJC Scopus subject areas
- Hematology
Fingerprint Dive into the research topics of 'Ageing of rabbit red cells in vitro: Membrane modifications and their possible role in red cell survival in vivo'. Together they form a unique fingerprint.
Cite this
Balduini, C. L., Sinigaglia, F., Ascari, E., & Balduini, C. (1981). Ageing of rabbit red cells in vitro: Membrane modifications and their possible role in red cell survival in vivo. Acta Haematologica, 65(4), 263-269.