A multi-centre study revealed a total of 67 epileptic subjects affected by Agenesis of the corpus callosum (ACC). We decided to study the etiological, clinical and evolutive aspects of the epileptic seizures. Cases affected by Aicardi's syndrome were excluded. The most important results are that there is no clinical expression epilepsy form of ACC; all forms of epilepsy may be present as can all types of seizures but secondary generalized epilepsies are much more frequent even when brain damage is not associated with ACC; non-classificable epileptic forms are present only when there is associated brain damage and in this case ACC is often total; partial epilepsies are not prevalent in case of ACC but cases with hemi-generalized seizures only are frequent; there is a high incidence of status epilepticus; the evolution of the seizures being a dependent syndrome and not conditioned by the ACC although asymptomatic cases of ACC have been reported; epilepsy is more frequent in subjects affected by ACC than in normal subjects.
|Translated title of the contribution||Agenesis of the corpus callosum and epilepsy (except Aicardi's syndrome)|
|Number of pages||10|
|Journal||Bollettino - Lega Italiana contro l'Epilessia|
|Publication status||Published - 1984|
ASJC Scopus subject areas
- Clinical Neurology