Aggregation properties of semisynthetic GM1 ganglioside (II3Neu5AcGgOse4Cer) containing an acetyl group as acyl moiety

Sandro Sonnino, Laura Cantu', Mario Corti, Domenico Acquotti, Gunther Kirschner, Guido Tettamanti

Research output: Contribution to journalArticle

32 Citations (Scopus)

Abstract

The aggregative properties of GM1 ganglioside containing an acetyl group as acyl moiety [GM1(acetyl)] in aqueous solution have been studied by static and dynamic light scattering measurements and surface tension experiments. GM1 (acetyl) spontaneously aggregates as small micelles showing a hydrodynamic radius and molecular weight of 34 Å and 102 kDa, respectively, down to a concentration of 2.0 × 10-5 M.

Original languageEnglish
Pages (from-to)49-57
Number of pages9
JournalChemistry and Physics of Lipids
Volume56
Issue number1
DOIs
Publication statusPublished - 1990

Fingerprint

G(M1) Ganglioside
Surface Tension
Micelles
Dynamic light scattering
Hydrodynamics
Surface tension
Agglomeration
Molecular Weight
Molecular weight
Experiments
Dynamic Light Scattering

Keywords

  • c.m.c.
  • ganglioside aggregates
  • ganglioside derivatives
  • gangliosides
  • light scattering
  • micelles
  • surface tension

ASJC Scopus subject areas

  • Biochemistry
  • Biophysics

Cite this

Aggregation properties of semisynthetic GM1 ganglioside (II3Neu5AcGgOse4Cer) containing an acetyl group as acyl moiety. / Sonnino, Sandro; Cantu', Laura; Corti, Mario; Acquotti, Domenico; Kirschner, Gunther; Tettamanti, Guido.

In: Chemistry and Physics of Lipids, Vol. 56, No. 1, 1990, p. 49-57.

Research output: Contribution to journalArticle

Sonnino, Sandro ; Cantu', Laura ; Corti, Mario ; Acquotti, Domenico ; Kirschner, Gunther ; Tettamanti, Guido. / Aggregation properties of semisynthetic GM1 ganglioside (II3Neu5AcGgOse4Cer) containing an acetyl group as acyl moiety. In: Chemistry and Physics of Lipids. 1990 ; Vol. 56, No. 1. pp. 49-57.
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