Aggregation properties of semisynthetic GM1 ganglioside (II3Neu5AcGgOse4Cer) containing an acetyl group as acyl moiety

Sandro Sonnino, Laura Cantu', Mario Corti, Domenico Acquotti, Gunther Kirschner, Guido Tettamanti

Research output: Contribution to journal › Article

32 Citations (Scopus)

Abstract

The aggregative properties of GM1 ganglioside containing an acetyl group as acyl moiety [GM1(acetyl)] in aqueous solution have been studied by static and dynamic light scattering measurements and surface tension experiments. GM1 (acetyl) spontaneously aggregates as small micelles showing a hydrodynamic radius and molecular weight of 34 Å and 102 kDa, respectively, down to a concentration of 2.0 × 10-5 M.

Original languageEnglish
Pages (from-to)49-57
Number of pages9
JournalChemistry and Physics of Lipids
Volume56
Issue number1
DOIs
Publication statusPublished - 1990

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G(M1) Ganglioside
Surface Tension
Micelles
Dynamic light scattering
Hydrodynamics
Surface tension
Agglomeration
Molecular Weight
Molecular weight
Experiments
Dynamic Light Scattering

Keywords

  • c.m.c.
  • ganglioside aggregates
  • ganglioside derivatives
  • gangliosides
  • light scattering
  • micelles
  • surface tension

ASJC Scopus subject areas

  • Biochemistry
  • Biophysics

Cite this

Aggregation properties of semisynthetic GM1 ganglioside (II3Neu5AcGgOse4Cer) containing an acetyl group as acyl moiety. / Sonnino, Sandro; Cantu', Laura; Corti, Mario; Acquotti, Domenico; Kirschner, Gunther; Tettamanti, Guido.

In: Chemistry and Physics of Lipids, Vol. 56, No. 1, 1990, p. 49-57.

Research output: Contribution to journal › Article

Sonnino, S, Cantu', L, Corti, M, Acquotti, D, Kirschner, G & Tettamanti, G 1990, 'Aggregation properties of semisynthetic GM1 ganglioside (II3Neu5AcGgOse4Cer) containing an acetyl group as acyl moiety', Chemistry and Physics of Lipids, vol. 56, no. 1, pp. 49-57. https://doi.org/10.1016/0009-3084(90)90087-8
Sonnino S, Cantu' L, Corti M, Acquotti D, Kirschner G, Tettamanti G. Aggregation properties of semisynthetic GM1 ganglioside (II3Neu5AcGgOse4Cer) containing an acetyl group as acyl moiety. Chemistry and Physics of Lipids. 1990;56(1):49-57. https://doi.org/10.1016/0009-3084(90)90087-8
Sonnino, Sandro ; Cantu', Laura ; Corti, Mario ; Acquotti, Domenico ; Kirschner, Gunther ; Tettamanti, Guido. / Aggregation properties of semisynthetic GM1 ganglioside (II3Neu5AcGgOse4Cer) containing an acetyl group as acyl moiety. In: Chemistry and Physics of Lipids. 1990 ; Vol. 56, No. 1. pp. 49-57.
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