Abstract
Osteosarcoma of the craniofacial bones (CFOS) usually behaves less aggressively than appendicular skeleton OS, resulting in a better therapeutic response to either surgery alone or multi-modality treatment. Here we report the case of a 54-year old male diagnosed with high-grade chondroblastic OS of the mandible, who presented with painful swelling of the horizontal branch of the right mandible, accompanied by paresthesias and paroxystic pain episodes. The patient was treated with aggressive surgery and adjuvant chemotherapy but, despite favorable clinical prognostic factors, disease rapidly progressed to local and distant relapse, causing the patient's death 18 months after diagnosis.
| Original language | English |
|---|---|
| Pages (from-to) | 296-298 |
| Number of pages | 3 |
| Journal | Oral Oncology Extra |
| Volume | 41 |
| Issue number | 10 |
| DOIs | |
| Publication status | Published - Nov 2005 |
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Keywords
- Chondroblastic
- Craniofacial bones
- Mandible
- Osteosarcoma
ASJC Scopus subject areas
- Otorhinolaryngology
- Oncology
- Oral Surgery
- Pathology and Forensic Medicine
Cite this
Aggressive chondroblastic osteosarcoma of the jawbone. / De Biase, Alberto; Morciano, Walter; Carpino, Francesco; Milella, Michele.
In: Oral Oncology Extra, Vol. 41, No. 10, 11.2005, p. 296-298.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Aggressive chondroblastic osteosarcoma of the jawbone
AU - De Biase, Alberto
AU - Morciano, Walter
AU - Carpino, Francesco
AU - Milella, Michele
PY - 2005/11
Y1 - 2005/11
N2 - Osteosarcoma of the craniofacial bones (CFOS) usually behaves less aggressively than appendicular skeleton OS, resulting in a better therapeutic response to either surgery alone or multi-modality treatment. Here we report the case of a 54-year old male diagnosed with high-grade chondroblastic OS of the mandible, who presented with painful swelling of the horizontal branch of the right mandible, accompanied by paresthesias and paroxystic pain episodes. The patient was treated with aggressive surgery and adjuvant chemotherapy but, despite favorable clinical prognostic factors, disease rapidly progressed to local and distant relapse, causing the patient's death 18 months after diagnosis.
AB - Osteosarcoma of the craniofacial bones (CFOS) usually behaves less aggressively than appendicular skeleton OS, resulting in a better therapeutic response to either surgery alone or multi-modality treatment. Here we report the case of a 54-year old male diagnosed with high-grade chondroblastic OS of the mandible, who presented with painful swelling of the horizontal branch of the right mandible, accompanied by paresthesias and paroxystic pain episodes. The patient was treated with aggressive surgery and adjuvant chemotherapy but, despite favorable clinical prognostic factors, disease rapidly progressed to local and distant relapse, causing the patient's death 18 months after diagnosis.
KW - Chondroblastic
KW - Craniofacial bones
KW - Mandible
KW - Osteosarcoma
UR - http://www.scopus.com/inward/record.url?scp=27644551300&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=27644551300&partnerID=8YFLogxK
U2 - 10.1016/j.ooe.2005.07.006
DO - 10.1016/j.ooe.2005.07.006
M3 - Article
AN - SCOPUS:27644551300
VL - 41
SP - 296
EP - 298
JO - Oral Oncology Extra
JF - Oral Oncology Extra
SN - 1741-9409
IS - 10
ER -