Aggressive chondroblastic osteosarcoma of the jawbone

Alberto De Biase, Walter Morciano, Francesco Carpino, Michele Milella

Research output: Contribution to journalArticlepeer-review


Osteosarcoma of the craniofacial bones (CFOS) usually behaves less aggressively than appendicular skeleton OS, resulting in a better therapeutic response to either surgery alone or multi-modality treatment. Here we report the case of a 54-year old male diagnosed with high-grade chondroblastic OS of the mandible, who presented with painful swelling of the horizontal branch of the right mandible, accompanied by paresthesias and paroxystic pain episodes. The patient was treated with aggressive surgery and adjuvant chemotherapy but, despite favorable clinical prognostic factors, disease rapidly progressed to local and distant relapse, causing the patient's death 18 months after diagnosis.

Original languageEnglish
Pages (from-to)296-298
Number of pages3
JournalOral Oncology Extra
Issue number10
Publication statusPublished - Nov 2005


  • Chondroblastic
  • Craniofacial bones
  • Mandible
  • Osteosarcoma

ASJC Scopus subject areas

  • Otorhinolaryngology
  • Oncology
  • Oral Surgery
  • Pathology and Forensic Medicine


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