Abstract
The concept of Agrypnia excitata (AE) was originally proposed as a concept deriving from the clinical and anatomo-pathological observations obtained in three different diseases, Fatal familial insomnia (FFI), Delirium tremens (DT), and Morvan syndrome (MS). Agrypnia refers to a condition of severely reduced or absent sleep due to organic disorders. Excitata refers to the association of agrypnia with generalized motor and autonomic hyperactivation. AE is a syndrome that has been claimed to relate to a dysfunction in the thalamo-limbic circuits that govern sleep-wake cycles and autonomic activities.
Original language | English |
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Journal | Sleep Medicine |
Volume | 12 |
Issue number | SUPPL. 2 |
DOIs | |
Publication status | Published - Dec 2011 |
Keywords
- Agrypnia excitata
- Delirium tremens
- Fatal familial insomnia
- Morvan syndrome
- Sleep loss
- Thalamus
ASJC Scopus subject areas
- Medicine(all)