Agrypnia excitata

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The concept of Agrypnia excitata (AE) was originally proposed as a concept deriving from the clinical and anatomo-pathological observations obtained in three different diseases, Fatal familial insomnia (FFI), Delirium tremens (DT), and Morvan syndrome (MS). Agrypnia refers to a condition of severely reduced or absent sleep due to organic disorders. Excitata refers to the association of agrypnia with generalized motor and autonomic hyperactivation. AE is a syndrome that has been claimed to relate to a dysfunction in the thalamo-limbic circuits that govern sleep-wake cycles and autonomic activities.

Original languageEnglish
JournalSleep Medicine
Issue numberSUPPL. 2
Publication statusPublished - Dec 2011


  • Agrypnia excitata
  • Delirium tremens
  • Fatal familial insomnia
  • Morvan syndrome
  • Sleep loss
  • Thalamus

ASJC Scopus subject areas

  • Medicine(all)


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