Il monitoraggio ambientale e biologico dell'esposizione professionale a gas anestetici presso le sale operatorie di un grande ospedale Milanese

Translated title of the contribution: Air and biomonitoring of occupational exposure to anesthetic gases in the health care workers of a large hospital in Milan

S. Fustinoni, R. Pasini, F. Strangi, C. Valla, P. Missineo, M. Margonari, R. Denaro, P. A. Bertazzi

Research output: Contribution to journalArticle


In this study exposure to anesthetic gases in health care workers of a hospital of Milan was investigated. The evaluation focused on the period 2007-2010 and was performed by environmental monitoring (20 operating rooms and 54 samples) and biological monitoring (180 workers and 242 urine samples). Mean airborne exposure was 3:15 and 0.34 ppm for nitrogen protoxide (N20) and sevorane; in end-of-exposure urine samples the concentration of N 20 and hexafluoroisopropanol, metabolite of sevorane, were 4.85 mg/L and 0.21 mg/L, with 80 and 21% of values below the quantification limit. Sevorane monitoring exceeded or equaled the environmental limit value of 0.5 ppm and the biological exposure index in 17 and 11% of measures. There were no observed exceedances of the limit for N20. The anesthetist and scrub nurse were tasks with greater exposure. There was a significant correlation between airborne halogenated gases and urinary hexafluoroisopropanol. The results of this study indicates that further efforts are needed to improve the hygienic conditions in the investigated hospital.

Original languageItalian
Pages (from-to)278-279
Number of pages2
JournalGiornale Italiano di Medicina del Lavoro ed Ergonomia
Issue number3
Publication statusPublished - Jul 2012


ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health

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