Abstract
The relationship between liver disease and pregnancy is of great clinical impact. Severe liver disease in pregnancy is rare; however, pregnancy-related liver disease is the most frequent cause of liver dysfunction during pregnancy and represents a severe threat to foetal and maternal survival. A rapid differential diagnosis between liver disease related or unrelated to pregnancy is required in women who present with liver dysfunction during pregnancy. This report summarizes the recommendation of an expert panel established by the Italian Association for the Study of the Liver (AISF) on the management of liver disease during pregnancy. The article provides an overview of liver disease occurring in pregnancy, an update on the key mechanisms involved in its pathogenesis, and an assessment of the available treatment options. The report contains in three sections: (1) specific liver diseases of pregnancy; (2) liver disease occurring during pregnancy; and (3) pregnancy in patients with pre-existing chronic liver disease. Each topic is discussed considering the most relevant data available in literature; the final statements are formulated according to both scientific evidence and clinical expertise of the involved physicians, and the AISF expert panel recommendations are reported.
| Original language | English |
|---|---|
| Pages (from-to) | 120-137 |
| Number of pages | 18 |
| Journal | Digestive and Liver Disease |
| Volume | 48 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - Feb 1 2016 |
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Keywords
- Liver diseases
- Pregnancy
ASJC Scopus subject areas
- Gastroenterology
- Hepatology
Cite this
AISF position paper on liver disease and pregnancy. / Morisco, Filomena; Bruno, Raffaele; Bugianesi, Elisabetta; Burra, Patrizia; Calvaruso, Vincenza; Cannoni, Alice; Caporaso, Nicola; Caviglia, Gian Paolo; Ciancio, Alessia; Fargion, Silvia; Federico, Alessandro; Floreani, Annarosa; Gaeta, Giovanni Battista; Guarino, Maria; Invernizzi, Pietro; Licata, Anna; Loguercio, Carmela; Mazzella, Giuseppe; Petraglia, Felice; Primignani, Massimo; Rodriguez-Castro, Kryssia; Smedile, Antonina; Valenti, Luca; Vannic, Ester; Vannuccini, Silvia; Voltolini, Chiara; Villao, Erica.
In: Digestive and Liver Disease, Vol. 48, No. 2, 01.02.2016, p. 120-137.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - AISF position paper on liver disease and pregnancy
AU - Morisco, Filomena
AU - Bruno, Raffaele
AU - Bugianesi, Elisabetta
AU - Burra, Patrizia
AU - Calvaruso, Vincenza
AU - Cannoni, Alice
AU - Caporaso, Nicola
AU - Caviglia, Gian Paolo
AU - Ciancio, Alessia
AU - Fargion, Silvia
AU - Federico, Alessandro
AU - Floreani, Annarosa
AU - Gaeta, Giovanni Battista
AU - Guarino, Maria
AU - Invernizzi, Pietro
AU - Licata, Anna
AU - Loguercio, Carmela
AU - Mazzella, Giuseppe
AU - Petraglia, Felice
AU - Primignani, Massimo
AU - Rodriguez-Castro, Kryssia
AU - Smedile, Antonina
AU - Valenti, Luca
AU - Vannic, Ester
AU - Vannuccini, Silvia
AU - Voltolini, Chiara
AU - Villao, Erica
PY - 2016/2/1
Y1 - 2016/2/1
N2 - The relationship between liver disease and pregnancy is of great clinical impact. Severe liver disease in pregnancy is rare; however, pregnancy-related liver disease is the most frequent cause of liver dysfunction during pregnancy and represents a severe threat to foetal and maternal survival. A rapid differential diagnosis between liver disease related or unrelated to pregnancy is required in women who present with liver dysfunction during pregnancy. This report summarizes the recommendation of an expert panel established by the Italian Association for the Study of the Liver (AISF) on the management of liver disease during pregnancy. The article provides an overview of liver disease occurring in pregnancy, an update on the key mechanisms involved in its pathogenesis, and an assessment of the available treatment options. The report contains in three sections: (1) specific liver diseases of pregnancy; (2) liver disease occurring during pregnancy; and (3) pregnancy in patients with pre-existing chronic liver disease. Each topic is discussed considering the most relevant data available in literature; the final statements are formulated according to both scientific evidence and clinical expertise of the involved physicians, and the AISF expert panel recommendations are reported.
AB - The relationship between liver disease and pregnancy is of great clinical impact. Severe liver disease in pregnancy is rare; however, pregnancy-related liver disease is the most frequent cause of liver dysfunction during pregnancy and represents a severe threat to foetal and maternal survival. A rapid differential diagnosis between liver disease related or unrelated to pregnancy is required in women who present with liver dysfunction during pregnancy. This report summarizes the recommendation of an expert panel established by the Italian Association for the Study of the Liver (AISF) on the management of liver disease during pregnancy. The article provides an overview of liver disease occurring in pregnancy, an update on the key mechanisms involved in its pathogenesis, and an assessment of the available treatment options. The report contains in three sections: (1) specific liver diseases of pregnancy; (2) liver disease occurring during pregnancy; and (3) pregnancy in patients with pre-existing chronic liver disease. Each topic is discussed considering the most relevant data available in literature; the final statements are formulated according to both scientific evidence and clinical expertise of the involved physicians, and the AISF expert panel recommendations are reported.
KW - Liver diseases
KW - Pregnancy
UR - http://www.scopus.com/inward/record.url?scp=84952362156&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84952362156&partnerID=8YFLogxK
U2 - 10.1016/j.dld.2015.11.004
DO - 10.1016/j.dld.2015.11.004
M3 - Article
VL - 48
SP - 120
EP - 137
JO - Digestive and Liver Disease
JF - Digestive and Liver Disease
SN - 1590-8658
IS - 2
ER -