Albumin administration in the acutely ill

What is new and where next?

Jean Louis Vincent, James A. Russell, Matthias Jacob, Greg Martin, Bertrand Guidet, Jan Wernerman, Ricard F. Roca, Stuart A. McCluskey, Luciano Gattinoni

Research output: Contribution to journalArticle

46 Citations (Scopus)

Abstract

Albumin solutions have been used worldwide for the treatment of critically ill patients since they became commercially available in the 1940s. However, their use has become the subject of criticism and debate in more recent years. Importantly, all fluid solutions have potential benefits and drawbacks. Large multicenter randomized studies have provided valuable data regarding the safety of albumin solutions, and have begun to clarify which groups of patients are most likely to benefit from their use. However, many questions remain related to where exactly albumin fits within our fluid choices. Here, we briefly summarize some of the physiology and history of albumin use in intensive care before offering some evidence-based guidance for albumin use in critically ill patients.

Original languageEnglish
Article number231
JournalCritical Care
Volume18
Issue number4
DOIs
Publication statusPublished - Jul 16 2014

Fingerprint

Albumins
Critical Illness
Critical Care
Multicenter Studies
Safety
Therapeutics

ASJC Scopus subject areas

  • Critical Care and Intensive Care Medicine

Cite this

Vincent, J. L., Russell, J. A., Jacob, M., Martin, G., Guidet, B., Wernerman, J., ... Gattinoni, L. (2014). Albumin administration in the acutely ill: What is new and where next? Critical Care, 18(4), [231]. https://doi.org/10.1186/cc13991

Albumin administration in the acutely ill : What is new and where next? / Vincent, Jean Louis; Russell, James A.; Jacob, Matthias; Martin, Greg; Guidet, Bertrand; Wernerman, Jan; Roca, Ricard F.; McCluskey, Stuart A.; Gattinoni, Luciano.

In: Critical Care, Vol. 18, No. 4, 231, 16.07.2014.

Research output: Contribution to journalArticle

Vincent, JL, Russell, JA, Jacob, M, Martin, G, Guidet, B, Wernerman, J, Roca, RF, McCluskey, SA & Gattinoni, L 2014, 'Albumin administration in the acutely ill: What is new and where next?', Critical Care, vol. 18, no. 4, 231. https://doi.org/10.1186/cc13991
Vincent JL, Russell JA, Jacob M, Martin G, Guidet B, Wernerman J et al. Albumin administration in the acutely ill: What is new and where next? Critical Care. 2014 Jul 16;18(4). 231. https://doi.org/10.1186/cc13991
Vincent, Jean Louis ; Russell, James A. ; Jacob, Matthias ; Martin, Greg ; Guidet, Bertrand ; Wernerman, Jan ; Roca, Ricard F. ; McCluskey, Stuart A. ; Gattinoni, Luciano. / Albumin administration in the acutely ill : What is new and where next?. In: Critical Care. 2014 ; Vol. 18, No. 4.
@article{2e0fb1a4da264e408baa3881cada63fc,
title = "Albumin administration in the acutely ill: What is new and where next?",
abstract = "Albumin solutions have been used worldwide for the treatment of critically ill patients since they became commercially available in the 1940s. However, their use has become the subject of criticism and debate in more recent years. Importantly, all fluid solutions have potential benefits and drawbacks. Large multicenter randomized studies have provided valuable data regarding the safety of albumin solutions, and have begun to clarify which groups of patients are most likely to benefit from their use. However, many questions remain related to where exactly albumin fits within our fluid choices. Here, we briefly summarize some of the physiology and history of albumin use in intensive care before offering some evidence-based guidance for albumin use in critically ill patients.",
author = "Vincent, {Jean Louis} and Russell, {James A.} and Matthias Jacob and Greg Martin and Bertrand Guidet and Jan Wernerman and Roca, {Ricard F.} and McCluskey, {Stuart A.} and Luciano Gattinoni",
year = "2014",
month = "7",
day = "16",
doi = "10.1186/cc13991",
language = "English",
volume = "18",
journal = "Critical Care",
issn = "1466-609X",
publisher = "Springer Science + Business Media",
number = "4",

}

TY - JOUR

T1 - Albumin administration in the acutely ill

T2 - What is new and where next?

AU - Vincent, Jean Louis

AU - Russell, James A.

AU - Jacob, Matthias

AU - Martin, Greg

AU - Guidet, Bertrand

AU - Wernerman, Jan

AU - Roca, Ricard F.

AU - McCluskey, Stuart A.

AU - Gattinoni, Luciano

PY - 2014/7/16

Y1 - 2014/7/16

N2 - Albumin solutions have been used worldwide for the treatment of critically ill patients since they became commercially available in the 1940s. However, their use has become the subject of criticism and debate in more recent years. Importantly, all fluid solutions have potential benefits and drawbacks. Large multicenter randomized studies have provided valuable data regarding the safety of albumin solutions, and have begun to clarify which groups of patients are most likely to benefit from their use. However, many questions remain related to where exactly albumin fits within our fluid choices. Here, we briefly summarize some of the physiology and history of albumin use in intensive care before offering some evidence-based guidance for albumin use in critically ill patients.

AB - Albumin solutions have been used worldwide for the treatment of critically ill patients since they became commercially available in the 1940s. However, their use has become the subject of criticism and debate in more recent years. Importantly, all fluid solutions have potential benefits and drawbacks. Large multicenter randomized studies have provided valuable data regarding the safety of albumin solutions, and have begun to clarify which groups of patients are most likely to benefit from their use. However, many questions remain related to where exactly albumin fits within our fluid choices. Here, we briefly summarize some of the physiology and history of albumin use in intensive care before offering some evidence-based guidance for albumin use in critically ill patients.

UR - http://www.scopus.com/inward/record.url?scp=84904332258&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84904332258&partnerID=8YFLogxK

U2 - 10.1186/cc13991

DO - 10.1186/cc13991

M3 - Article

VL - 18

JO - Critical Care

JF - Critical Care

SN - 1466-609X

IS - 4

M1 - 231

ER -