Alcohol- and Substance-Dependent Subjects: The Correlated Factors in Qualifying for Liver Transplantation

L. Gallimberti, G. Forza, P. Angeli, A. Vitale, U. Cillo, A. Gatta, D. D'Amico

Research output: Contribution to journalArticle

Abstract

Objectives: To identify the most significant variables in determining if candidates with past or current addictions can be considered for liver transplantation. Methods: Data relating to 58 cases from January 2001 to December 2003 were collected and analyzed. Results: The decisional algorithm identified by discriminant analysis is based on the following variables: the duration of remission, treatment adherence, and the presence of a valid help relationship. Candidates undergoing initial remission (up to 12 months) must demonstrate both adherence and affective support; those with over 5 years of remission, however, are considered sufficiently reliable. A positive judgment is significantly correlated to overall survival and clinical improvement even without transplantation. Conclusions: In toxicological evaluation, treatment adherence and the presence of a valid help relationship for patients in remission from addictions can improve the selection criteria for liver transplantation, making it more dependable.

Original languageEnglish
Pages (from-to)1861-1863
Number of pages3
JournalTransplantation Proceedings
Volume39
Issue number6
DOIs
Publication statusPublished - Jul 2007

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Liver Transplantation
Alcohols
Discriminant Analysis
Toxicology
Patient Selection
Transplantation
Survival
Therapeutics

ASJC Scopus subject areas

  • Surgery
  • Transplantation

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Alcohol- and Substance-Dependent Subjects : The Correlated Factors in Qualifying for Liver Transplantation. / Gallimberti, L.; Forza, G.; Angeli, P.; Vitale, A.; Cillo, U.; Gatta, A.; D'Amico, D.

In: Transplantation Proceedings, Vol. 39, No. 6, 07.2007, p. 1861-1863.

Research output: Contribution to journalArticle

Gallimberti, L, Forza, G, Angeli, P, Vitale, A, Cillo, U, Gatta, A & D'Amico, D 2007, 'Alcohol- and Substance-Dependent Subjects: The Correlated Factors in Qualifying for Liver Transplantation', Transplantation Proceedings, vol. 39, no. 6, pp. 1861-1863. https://doi.org/10.1016/j.transproceed.2007.05.024
Gallimberti, L. ; Forza, G. ; Angeli, P. ; Vitale, A. ; Cillo, U. ; Gatta, A. ; D'Amico, D. / Alcohol- and Substance-Dependent Subjects : The Correlated Factors in Qualifying for Liver Transplantation. In: Transplantation Proceedings. 2007 ; Vol. 39, No. 6. pp. 1861-1863.
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