Alcohol and wine in relation to cancer and other diseases

Attilio Giacosa; Anne F. Adam-Blondon; Sara Baer-Sinnott; Roberto Barale; Luigi Bavaresco; Gabriele Di Gaspero; Laura Dugo; Robert Curtis Ellison; Vincenzo Gerbi; Dun Gifford; Jaak Janssens; Carlo La Vecchia; Eva Negri; Mario Pezzotti; Leonardo Santi; Luca Santi; Mariangela Rondanelli

doi:10.1097/CEJ.0b013e32834761d3

Alcohol and wine in relation to cancer and other diseases

Attilio Giacosa, Anne F. Adam-Blondon, Sara Baer-Sinnott, Roberto Barale, Luigi Bavaresco, Gabriele Di Gaspero, Laura Dugo, Robert Curtis Ellison, Vincenzo Gerbi, Dun Gifford, Jaak Janssens, Carlo La Vecchia, Eva Negri, Mario Pezzotti, Leonardo Santi, Luca Santi, Mariangela Rondanelli

Istituto di Ricerche Farmacologiche "Mario Negri"

Research output: Contribution to journal › Article › peer-review

Abstract

Heavy alcohol consumption is associated with increased overall mortality, cancer, liver, and cardiovascular diseases; but low doses of alcohol (up to one drink per day) are not associated with the risk of any cancer site with the exception of breast cancer and possibly of oral and pharyngeal cancers. Moreover, recent evidence indicates that moderate alcohol and specifically wine intake provides cardioprotection and neuroprotection and may increase longevity. Various experimental data hypothesize a potential cancer chemopreventive role of some grape extracts, and complete sequencing of the grapevine genome has revealed genes responsible for the synthesis of health-promoting compounds (resveratrol and other polyphenols), thus advocating the development of future potential nutraceutical strategies. This focuses on the pros and cons of moderate alcohol and wine consumption and opens a debate on this topic.

Original language	English
Pages (from-to)	103-108
Number of pages	6
Journal	European Journal of Cancer Prevention
Volume	21
Issue number	1
DOIs	https://doi.org/10.1097/CEJ.0b013e32834761d3
Publication status	Published - Jan 2012

Keywords

Alcohol
Cancer
Genomics
Polyphenols
Resveratrol
Wine

ASJC Scopus subject areas

Cancer Research
Oncology
Epidemiology
Public Health, Environmental and Occupational Health

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Giacosa, A., Adam-Blondon, A. F., Baer-Sinnott, S., Barale, R., Bavaresco, L., Di Gaspero, G., Dugo, L., Curtis Ellison, R., Gerbi, V., Gifford, D., Janssens, J., La Vecchia, C., Negri, E., Pezzotti, M., Santi, L., Santi, L., & Rondanelli, M. (2012). Alcohol and wine in relation to cancer and other diseases. European Journal of Cancer Prevention, 21(1), 103-108. https://doi.org/10.1097/CEJ.0b013e32834761d3

Alcohol and wine in relation to cancer and other diseases. / Giacosa, Attilio; Adam-Blondon, Anne F.; Baer-Sinnott, Sara; Barale, Roberto; Bavaresco, Luigi; Di Gaspero, Gabriele; Dugo, Laura; Curtis Ellison, Robert; Gerbi, Vincenzo; Gifford, Dun; Janssens, Jaak; La Vecchia, Carlo; Negri, Eva; Pezzotti, Mario; Santi, Leonardo; Santi, Luca; Rondanelli, Mariangela.

In: European Journal of Cancer Prevention, Vol. 21, No. 1, 01.2012, p. 103-108.

Research output: Contribution to journal › Article › peer-review

Giacosa, A, Adam-Blondon, AF, Baer-Sinnott, S, Barale, R, Bavaresco, L, Di Gaspero, G, Dugo, L, Curtis Ellison, R, Gerbi, V, Gifford, D, Janssens, J, La Vecchia, C, Negri, E, Pezzotti, M, Santi, L, Santi, L & Rondanelli, M 2012, 'Alcohol and wine in relation to cancer and other diseases', European Journal of Cancer Prevention, vol. 21, no. 1, pp. 103-108. https://doi.org/10.1097/CEJ.0b013e32834761d3

Giacosa, Attilio ; Adam-Blondon, Anne F. ; Baer-Sinnott, Sara ; Barale, Roberto ; Bavaresco, Luigi ; Di Gaspero, Gabriele ; Dugo, Laura ; Curtis Ellison, Robert ; Gerbi, Vincenzo ; Gifford, Dun ; Janssens, Jaak ; La Vecchia, Carlo ; Negri, Eva ; Pezzotti, Mario ; Santi, Leonardo ; Santi, Luca ; Rondanelli, Mariangela. / Alcohol and wine in relation to cancer and other diseases. In: European Journal of Cancer Prevention. 2012 ; Vol. 21, No. 1. pp. 103-108.

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