Alcohol and wine in relation to cancer and other diseases

Attilio Giacosa, Anne F. Adam-Blondon, Sara Baer-Sinnott, Roberto Barale, Luigi Bavaresco, Gabriele Di Gaspero, Laura Dugo, Robert Curtis Ellison, Vincenzo Gerbi, Dun Gifford, Jaak Janssens, Carlo La Vecchia, Eva Negri, Mario Pezzotti, Leonardo Santi, Luca Santi, Mariangela Rondanelli

Research output: Contribution to journalArticle

30 Citations (Scopus)

Abstract

Heavy alcohol consumption is associated with increased overall mortality, cancer, liver, and cardiovascular diseases; but low doses of alcohol (up to one drink per day) are not associated with the risk of any cancer site with the exception of breast cancer and possibly of oral and pharyngeal cancers. Moreover, recent evidence indicates that moderate alcohol and specifically wine intake provides cardioprotection and neuroprotection and may increase longevity. Various experimental data hypothesize a potential cancer chemopreventive role of some grape extracts, and complete sequencing of the grapevine genome has revealed genes responsible for the synthesis of health-promoting compounds (resveratrol and other polyphenols), thus advocating the development of future potential nutraceutical strategies. This focuses on the pros and cons of moderate alcohol and wine consumption and opens a debate on this topic.

Original languageEnglish
Pages (from-to)103-108
Number of pages6
JournalEuropean Journal of Cancer Prevention
Volume21
Issue number1
DOIs
Publication statusPublished - Jan 2012

Fingerprint

Mouth Neoplasms
Wine
Alcohol Drinking
Alcohols
Pharyngeal Neoplasms
Vitis
Polyphenols
Liver Neoplasms
Dietary Supplements
Liver Diseases
Neoplasms
Cardiovascular Diseases
Genome
Breast Neoplasms
Mortality
Health
Genes
resveratrol
Neuroprotection

Keywords

  • Alcohol
  • Cancer
  • Genomics
  • Polyphenols
  • Resveratrol
  • Wine

ASJC Scopus subject areas

  • Cancer Research
  • Oncology
  • Epidemiology
  • Public Health, Environmental and Occupational Health

Cite this

Giacosa, A., Adam-Blondon, A. F., Baer-Sinnott, S., Barale, R., Bavaresco, L., Di Gaspero, G., ... Rondanelli, M. (2012). Alcohol and wine in relation to cancer and other diseases. European Journal of Cancer Prevention, 21(1), 103-108. https://doi.org/10.1097/CEJ.0b013e32834761d3

Alcohol and wine in relation to cancer and other diseases. / Giacosa, Attilio; Adam-Blondon, Anne F.; Baer-Sinnott, Sara; Barale, Roberto; Bavaresco, Luigi; Di Gaspero, Gabriele; Dugo, Laura; Curtis Ellison, Robert; Gerbi, Vincenzo; Gifford, Dun; Janssens, Jaak; La Vecchia, Carlo; Negri, Eva; Pezzotti, Mario; Santi, Leonardo; Santi, Luca; Rondanelli, Mariangela.

In: European Journal of Cancer Prevention, Vol. 21, No. 1, 01.2012, p. 103-108.

Research output: Contribution to journalArticle

Giacosa, A, Adam-Blondon, AF, Baer-Sinnott, S, Barale, R, Bavaresco, L, Di Gaspero, G, Dugo, L, Curtis Ellison, R, Gerbi, V, Gifford, D, Janssens, J, La Vecchia, C, Negri, E, Pezzotti, M, Santi, L, Santi, L & Rondanelli, M 2012, 'Alcohol and wine in relation to cancer and other diseases', European Journal of Cancer Prevention, vol. 21, no. 1, pp. 103-108. https://doi.org/10.1097/CEJ.0b013e32834761d3
Giacosa A, Adam-Blondon AF, Baer-Sinnott S, Barale R, Bavaresco L, Di Gaspero G et al. Alcohol and wine in relation to cancer and other diseases. European Journal of Cancer Prevention. 2012 Jan;21(1):103-108. https://doi.org/10.1097/CEJ.0b013e32834761d3
Giacosa, Attilio ; Adam-Blondon, Anne F. ; Baer-Sinnott, Sara ; Barale, Roberto ; Bavaresco, Luigi ; Di Gaspero, Gabriele ; Dugo, Laura ; Curtis Ellison, Robert ; Gerbi, Vincenzo ; Gifford, Dun ; Janssens, Jaak ; La Vecchia, Carlo ; Negri, Eva ; Pezzotti, Mario ; Santi, Leonardo ; Santi, Luca ; Rondanelli, Mariangela. / Alcohol and wine in relation to cancer and other diseases. In: European Journal of Cancer Prevention. 2012 ; Vol. 21, No. 1. pp. 103-108.
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