Alcohol consumption and risk of prostate cancer

A. Tavani, E. Negri, S. Franceschi, R. Talamini, C. La Vecchia

Research output: Contribution to journalArticle

Abstract

Because alcohol influences metabolism and serum levels of sex hormones and specifically increases metabolic clearance of testosterone, some role of alcohol consumption in the process of prostatic carcinogenesis is biologically plausible. The relationship between prostate cancer and total alcohol consumption was therefore investigated in a case-control study conducted in Northern Italy between 1985 and 1992 on 281 cases and 599 controls admitted to hospital for acute nonneoplastic diseases apparently unrelated to alcohol and tobacco consumption. No noteworthy relationship was found for major measures of alcohol intake: compared with teetotallers, the multivariate relative risks (RRs) of prostate cancer, after adjustment for age, study center, education, marital status, body mass index, and smoking status, were 1.3, 0.9, 1.2, and 1.1, respectively, for men drinking fewer than three, three to less than five, five to less than eight, or more than eight alcoholic beverages per day. None of the estimates was significant, nor was the trend in risk significant. Multivariate risks were also close to unity in the separate analysis of intake of wine (RR = 1.2 and 0.9 for

Original languageEnglish
Pages (from-to)25-31
Number of pages7
JournalNutrition and Cancer
Volume21
Issue number1
Publication statusPublished - 1994

ASJC Scopus subject areas

  • Food Science
  • Medicine (miscellaneous)
  • Oncology

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    Tavani, A., Negri, E., Franceschi, S., Talamini, R., & La Vecchia, C. (1994). Alcohol consumption and risk of prostate cancer. Nutrition and Cancer, 21(1), 25-31.