Alcohol intake and withdrawal: Effects on branched chain amino acids and alanine

A. Avogaro, M. Cibin, T. Croatto, A. Rizzo, L. Gallimberti, A. Tiengo

Research output: Contribution to journalArticlepeer-review


The effects of chronic alcohol consumption on plasma branched chain amino acids and alanine concentrations were evaluated, and basal blood concentrations of these amino acids were determined after chronic ethanol intake and following a withdrawal period in 30 admitted alcoholics. After ethanol intake, alcoholics showed increased branched chain amino acid concentrations; the blood alanine concentrations were depressed after the withdrawal period. To evaluate the effect of ethanol on diurnal variations of these amino acids in the blood, a group of these patients underwent two isocaloric diets with and without wine. The diet with alcohol induced a sustained increase of branched chain amino acids persisting even after the postprandial phase with a decrease of alanine as compared to the diet without.

Original languageEnglish
Pages (from-to)300-304
Number of pages5
JournalAlcoholism: Clinical and Experimental Research
Issue number3
Publication statusPublished - 1986

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Toxicology


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