Allergic manifestations in very low-birthweight infants: A 6-year follow-up

M. Agosti, C. Vegni, S. Gangi, V. Benedetti, A. Marini

Research output: Contribution to journalArticlepeer-review


The incidence of allergic manifestations was evaluated from birth until 6 y of age in 83 very low-birthweight infants (VLBWIs). In the same period 98 full-term babies were followed from birth to 24 mo of life. All the subjects were examined by paediatricians to establish the presence of atopic dermatitis (AD), gastrointestinal disturbances (GD) and asthma (AS). The incidence of total allergic manifestations (31.3%) in VLBWIs was significantly lower than that (52%) in 24-mo-old infants, born at full term. The incidence of allergies in VLBWIs did not differ at all at the subsequent checks, up to 6 y of age. AD (33.7%) was the most common symptom, statistically higher in full-term infants than in VLBWIs (7.2%). GD had a similar distribution (8.2% in fullterm infants vs 7.2% in VLBWIs). AS (16.8%) was significantly higher in VLBWIs than in those born full term (10.2%). In the various VLBWI subgroups analysed, AD was more prevalent in babies weighing >1000 g and in babies >30 wk of age; the incidence of GD was higher in infants weighing <1000 g and in SGA infants, and AS was more prevalent in infants weighing <1000 g, in infants

Original languageEnglish
Pages (from-to)44-47
Number of pages4
JournalActa Paediatrica, International Journal of Paediatrics, Supplement
Issue number441
Publication statusPublished - Sep 2003


  • Allergic manifestations
  • Full-term neonates
  • Premature babies

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health


Dive into the research topics of 'Allergic manifestations in very low-birthweight infants: A 6-year follow-up'. Together they form a unique fingerprint.

Cite this