Allergic subjects have more numerous respiratory infections and severe gastrointestinal infections than non-allergic subjects: Preliminary results

Giorgio Ciprandi, I. Cirillo, R. M. Troisi, G. L. Marseglia

Research output: Contribution to journalArticlepeer-review

Abstract

Allergic disorders are characterized by Th2-polarization, thus physiological Th1-dependent mechanisms for fighting infectious diseases (ID) may be defective. This study aims at evaluating the number and duration of respiratory (RI) and gastrointestinal diseases (GI) in allergic and non-allergic subjects in a particular community: the crew of an operative warship consisting of 189 persons (171 males and 18 females). The study period lasted for 5 months during an operative mission. The number and duration (days) of RI and GI were evaluated. Allergic subjects experienced more numerous RI (p=0.0029) and more severe GI (p=0.0001) than non-allergic subjects. This preliminary study provides evidence that allergic subjects may have more numerous RI and prolonged GI than non-allergic subjects.

Original languageEnglish
Pages (from-to)27-30
Number of pages4
JournalEuropean Journal of Inflammation
Volume5
Issue number1
Publication statusPublished - Jan 2007

Keywords

  • Allergy
  • Gastrointestinal infections
  • Respiratory infections
  • Th1 and Th2 cells

ASJC Scopus subject areas

  • Immunology

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