Allergy and Otitis Media in Clinical Practice: Current Allergy and Asthma Reports

G. Ciprandi, S. Torretta, G.L. Marseglia, A. Licari, E. Chiappini, M. Benazzo, M.A. Tosca, P. Marchisio

Research output: Contribution to journalArticlepeer-review


Purpose of Review: Otitis media (OM) is a disease with very high prevalence in infancy, substantial burden on healthcare resources, and relevant impact on the quality of life of families. The link between OM and allergy is controversial and still debated. However, a fundamental premise has to be placed before introducing this topic: there is the need to use clear and unambiguous terms. Literature abounds with misleading terms that significantly affect the methodology and consequently the outcomes. Moreover, it is essential to differentiate patients according to the OM type (i.e., acute OM, OM with effusion, and chronic suppurative OM), the allergic disease, and mainly the age. Recent Findings: There are some recent studies exploring this issue through different approaches, such as epidemiological, mechanistic, and therapeutic. To identify allergy as a pathogenic factor for OM could improve the management of OM patients. Vice versa, to suspect allergy in OM patients could be reasonable in selected patients. Summary: The current narrative review provides an overview of the evidence concerning the potential role of allergy in OM. As there are conflicting findings, a possible interpretation of pathophysiological events and a pragmatic approach are proposed. © 2020, Springer Science+Business Media, LLC, part of Springer Nature.
Original languageEnglish
JournalCurr. Allergy Asthma Rep.
Issue number8
Publication statusPublished - 2020


  • Acute otitis media
  • Allergy
  • Infections
  • Otitis media with effusion
  • Risk factors
  • Type 2 inflammation
  • acute otitis media
  • allergy
  • chronic suppurative otitis media
  • clinical practice
  • human
  • otitis media
  • recurrent disease
  • Review
  • secretory otitis media
  • adolescent
  • child
  • complication
  • hypersensitivity
  • preschool child
  • prevalence
  • psychology
  • quality of life
  • Adolescent
  • Child
  • Child, Preschool
  • Humans
  • Hypersensitivity
  • Otitis Media
  • Prevalence
  • Quality of Life


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